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沈松 副教授

 

职称:副教授

受教育经历

2010/09—2014/03,浙江大学药学院,博士

2003/09—2007/06,江苏大学药学院,硕士

1999/09—2003/07,江苏大学药学院,学士

 

研究方向

智能靶向载体的构建及评价

新型肿瘤治疗技术

肿瘤成像及诊断技术

 

在研项目

  1. 主持国家自然科学基金(81503017),pH/NIR双重智能响应系统靶向联合治疗类风湿关节炎的研究,2016.1-2018.12
  2. 主持江苏省自然科学基金(BK20150534),pH/NIR智能响应系统治疗类风湿关节炎的作用机制研究,2016.1-2018.12
  3. 主持中国博士后基金(一等资助2015M580404),基于氧化铁的诊断治疗系统在类风湿关节炎中的应用,2014.7-2016.6
  4. 主持江苏省博士后基金(1402075B),线粒体靶向给药系统的构建及其在肿瘤声动力治疗中的应用,2014.7-2016.6
  5. 主持江苏省高校自然科学基金(15KJB350001),基于Fe3O4的智能光控给药系统的构建及应用研究,2015.7-2017.6
  6. 主持江苏大学高级人才基金(14JDG181),Yolk-Shell结构的光触发释药系统的构建及其光热-化疗联合抗肿瘤应用研究,2014.7-2016.6

 

发表论文

[1] Song Shen, Xiaomeng Guo, Lin Wu, Meng Wang, Xinshi Wang, Fenfen Kong, Haijun Shen, Meng Xie, Yanru Ge, Yi Jin. Dual-core@shell-structured Fe3O4-NaYF4@TiO2 Nanocomposites as Magnetic Targeting Drug Carrier for Bioimaging and Combined Chemo-sonodynamic Therapy. J. Mater. Chem. B, 2014, 2, 5775. (IF: 4.8)

[2] Shen S, Kong FF, Guo XM, Wu L, Shen HJ, Xie M, Wang XS, Jin Yi*, Ge YR*. CMCTS stabilized Fe3O4 nanoparticles with extremely low toxicity as highly efficient near-infrared photothermal agents for in vivo tumor ablation. Nanoscale, 2013, 5, 8056–8066. (IF: 6.233)

[3] Song Shen, Lin Wu, Meng Xie, Haijun Shen, Xueyong Qi, Yongmin Yan, Yanru Ge and Yi Jin.Core-shell structured Fe3O4@TiO2 nanoparticles for targeted chemo-sonodynamic therapy of cancer. International Journal of Pharmaceutics, 2015, 486, 380–388 (IF: 3.785).

[4] Bei Ding, Song Shen*, Lin Wu, Xueyong Qi, Haihua Ni, Yanru Ge.Doxorubicin loaded Fe3O4@SiO2 nanoparticles as magnetic targeting agents for combined photothermal-chemotherapy of cancer. Chemistry letters, 2015, 6, 858-860 (IF: 1.4).

[5] Song Shen, Bei Ding, Lin Wu, Xueyong Qi, Yanru, Ge. Fe3O4@TiO2 nanocomposites for magnetic targeting sonodynamic therapy of cancer. Key Engineering Materials, 2015, 636: 129-132. (EI)

[6] Song Shen, Bei Ding, Qing Li, Xuwei Yu, Xueyong Qi, Yanru Ge. A novel chitosan microbubble as ultrasound-triggered drug carrier for antitumor in vitro. Key Engineering Materials, 2015, 636: 139-143. (EI)

[7] 沈松, 吴琳, 王成润, 戚雪勇, 戈延茹, 金一*. 载多柔比星磁性四氧化三铁的制备及体外评价. 药学学报, 2013, 48 (12): 1844 −1849.

[8] 沈松, 吴琳, 戚雪勇, 戈延茹, 金一*. 不同载体固体分散体对尼群地平和硝苯地平的增溶效果考察. 中国医药工业杂志, 2013, 44 (12): 1249-1252.

[9] 沈松, 吴琳, 戚雪勇, 戈延茹, 金一*. 磁性Fe3O4-羧甲基壳聚糖纳米粒的制备及光热性能研究. 中国药学杂志, 2014,49(16): 1432-1436.

[10] Xie M, Xu Y, Shen H, Shen S, Ge Y, Xie J. Negative-charge-functionalized mesoporous silica nanoparticles as drug vehicles targeting hepatocellular carcinoma. Int J Pharm., 2014, 474(1-2): 223-31.

[11] Li Z, li B, Wang M, Xie M, Shen HJ, Shen S, Wang XH, Guo XM, Yao MF, Jin Yi*. The role of endosome evasion bypass in the reversal of multidrug resistance by lipid/nanoparticle assemblies. J. Mater. Chem. B, 1: 1466-1474, 2013.  (IF: 6.101)

[12] Shen HJ, Shi H, Ma K, Xie M, Tang LL, Shen S, Li B, Wang XS, Jin Yi*. Polyelectrolyte capsules packaging BSA gels for pH-controlled drug loading and release and their antitumor activity. Acta Biomater. 2013, 9(4): 6123-6133. (IF: 5.093)

[13] Shen HJ, Shi H, Xie M, Ma K, Li B, Shen S, Wang XS, Jin Y*. Biodegradable chitosan/alginate BSA-gel-capsules for pH-controlled loading and release of doxorubicin and treatment of pulmonary melanoma. J. Mater. Chem. B, 2013,1, 3906-3917. (IF: 6.101)

[14] Xie M, Shi H, Zhen Li, Shen HJ, Ma K, Li B, Shen S, Jin Yi*.A multifunctional mesoporous silica nanocomposite for targeteddelivery, controlled release of doxorubicin and bioimaging. Colloids and Surfaces B: Biointerfaces, 2013, 110: 138-147. (IF: 3.554)

[15] Xie M, Shi H, Ma K, Shen HJ, Li B, Shen S, Wang X, Jin Yi*. Hybrid nanoparticles for drug delivery and bioimaging: Mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. J Colloid Interface Sci. Jan 10, 2013. (IF: 3.07)

[16] Li B, Xu H, Li Z, Yao M, Xie M, Shen HJ, Shen S, Wang XS, Jin Yi*. Bypassing multidrug resistance in human breast cancer cells with lipid/polymer particle assemblies. International Journal of Nanomedicine, 7: 187-197, 2012. (IF: 4.976)

[17] Ma K, Shen HJ, Shen S, Xie M, Mao CB, Qiu LY, Jin Yi*. Development o f a successive targeting liposome with multi-ligand for efficient targeting gene delivery. The Journal of Gene Medicine, 13: 290– 301, 2011. (IF: 3.079)