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芮蒙杰 副教授

受教育经历:

2005.09-2012.12,上海交通大学,生命科学技术学院,生物医学工程专业,博士,导师:徐宇虹教授

2001.09-2005.06,上海交通大学,生命科学技术学院,生物工程专业,学士

研究工作经历:

2017.7-至今,江苏大学,药学院,药剂教研室,副教授

2013.3-2017.6,江苏大学,药学院,药剂教研室,讲师

研究兴趣:

主要从事新型的多功能生物材料研究,通过结构设计和可控修饰得到模拟生物活性的大分子材料,在靶向药物输送、肿瘤治疗和多模态生物影像等多个领域进行综合应用。主要研究方向及兴趣包括:

1. 新型仿生纳米材料的开发及其在药物输送、治疗研究和生物成像上的应用

2. 多功能敏感型纳米材料在生物成像、肿瘤治疗与联合治疗上的应用

讲授课程:

制剂工程学

工业药剂学

Preparation Equipment and Process Design Workshop(海外教育学院)

Industrial Pharmaceutics(海外教育学院)

Pharmaceutical Molecular Biology(海外教育学院)

科研文章列表:

1. Chunlai Feng#, Mengjie Rui#, Haijun Shen, Yuanrong Xin, Jie Zhang, Jun Li, Lixiang Yue, Wenlong Lai, Ximing Xu*.Tumor-specific delivery of doxorubicin through conjugation of pH-responsive peptide for overcoming drug resistance in cancer, International Journal of Pharmaceutics, 2017, 528 (1-2):322-333.

2. Mengjie Rui#, Yuanrong Xin , Ran Li, Yanru Ge, Chunlai Feng*, and Ximing Xu*. Targeted Biomimetic Nanoparticles for Synergistic Combination Chemotherapy of Paclitaxel and Doxorubicin, Molecular Pharmaceutics, 2017, 14 (1): 107-123.

3. Mengjie Rui#, Yang Qu, Tong Gao, Yanru Ge, Chunlai Feng*, and Ximing Xu*. Simultaneous delivery of anti-miR21 with doxorubicin prodrug by mimetic lipoprotein nanoparticles for synergistic effect against drug resistance in cancer cells, International Journal of Nanomedicine, 2017, 12: 217-237.

4. Mengjie Rui#, Hailing Tang, Yan Li, Xiaohui Wei, and Yuhong Xu*. Recombinant High Density Lipoprotein Nanoparticles for Target-Specific Delivery of siRNA. Pharmaceutical research, 2013, 30 (5): 1203-14.

5. Mengjie Rui#, Wei Guo, Qian Ding, Xiaohui Wei, Jianrong Xu, and Yuhong Xu*. Recombinant high-density lipoprotein nanoparticles containing gadolinium-labeled cholesterol for morphologic and functional magnetic resonance imaging of the liver. International journal of nanomedicine. 2012, 7: 3751-3768.

6. Hailing Tang, Xiaojing Chen, Mengjie Rui, Wenqiang Sun, Jian Chen, Jinliang Peng, and Yuhong Xu*. Effects of surface displayed targeting ligand GE11 on liposome distribution and extravasation in tumor. Molecular Pharmaceutics, 2014, 11 (10): 3242–3250.

7. Yan Li, Mengjie Rui, Hailing Tang, and Yuhong Xu*. The distribution and cell uptake of ApoA1 modified lipid carriers of siRNA in mouse liver in vivo. Asian Journal of Pharmaceutical Sciences. 2013, 8: 228-233.

8. Junhua Mai, Shuxian Song, Mengjie Rui, Dan Liu, Qian Ding, Jinliang Peng, Yuhong Xu*. A synthetic peptide mediated active targeting of cisplatin liposomes to Tie2 expressing cells. Journal of Controlled Release. 2009, 139 (3): 174–181. 2009.

9. Xiaomeng Zhang*, Huanjun Yang*, Ke Gu, Jian Chen, Mengjie Rui, and Guo-Liang Jiang. In vitro and in vivo study of a nanoliposomal cisplatin as a radiosensitizer. International journal of nanomedicine. 2011, 6: 437-444.

联系方式:

办公室:江苏大学药学院2213室

E-mail: mjrui@ujs.edu.cn