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胡磊 教授

姓名:胡磊

性别:男

出生日期:1984年3月学历:博士研究生

邮箱:leihu@ujs.edu.cn毕业院校:瑞典皇家工学院

 

研究方向:动态组合化学,酶催化不对称合成

 

教育背景

2010.10至2014.10  博士瑞典皇家工学院 (KTH-Royal Institute of Technology) 有机化学

系,导师:Olof Ramström教授

2007.09至2010.06硕士暨南大学药学院药物化学专业,导师:陈卫民教授

2003.09至2007.06 本科湖南师范大学制药工程专业

 工作经历

2017.04至今江苏大学药学院,资格教授

2014.12至2016.08美国俄亥俄州立大学 (The Ohio State University) 化学系Jovica Badjic教授课题组博士后研究员

 科研成果

 Pratumyot, Y.; Chen, S.;Hu, L.; Polen, M. S.; Hadad, M. C.; Badjić, D. B. Assembly and folding of twisted baskets in organic solvents, Org. Lett., 2016, 18, 4238. 

Hu, L.;Polen, S.;Hardin, A.;Pratumyot, Y.;Hadad, C.;Badjić, J. On the Transfer of Chirality, Thermodynamic Stability, and Folding Characteristics of Stereoisomeric Gated Baskets. Eur. J. Org. Chem., 2015, 31, 6832. 

Hu, L.; Zhang, Y.; Ramström, O. Gelation-driven Dynamic Systemic Resolution: in situ Generation and Self-Selection of an Organogelator. Sci. Rep., 2015, 5, 11065. 

Hu, L.; Ren, Y., Ramström, O. Chirality Control in Enzyme-Catalyzed Dynamic Kinetic Resolution of 1,3-Oxathiolanes. J. Org. Chem., 2015, 80, 8478. 

Schaufelberger, F.; Hu, L.; Ramström, O.trans-Symmetric Dynamic Covalent Systems: Connected Transamination and Transimination Reactions. Chem. Eur. J., 2015, 21, 9776. 

Hu, L.; Ramström, O. Silver-catalyzed dynamic systemic resolution of α-iminonitriles in a 1,3-dipolar cycloaddition process. Chem. Commun., 2014, 50, 3792. 

Hu, L.; Zhang, Y.; Ramström, O. Lipase-catalyzed asymmetric synthesis of oxathiazinanones through dynamic covalent kinetic resolution. Org. Biomol. Chem., 2014, 12, 3572. 

Hu, L.; Schaufelberger, F.; Timmer, B. J. J.; Abellán Flos, M.; Ramström, O. Dynamic constitutional chemistry. In: Kirk-Othmer Encyclopedia of Chemical Technology., John Wiley & Sons, Inc., 2014.DOI: 10.1002/0471238961.consrams.a01 

Zhang, Y.; Hu, L.; Ramström, O. Constitutional dynamic chemistry for Bioactive Compounds. In: Supramolecular systems in biomedical fields. (Ed.: H.-J. Schneider) RSC, UK, 2013.(书籍章节) 

Hu, L.; Schaufelberger, F.; Zhang, Y.; Ramström, O. Efficient asymmetric synthesis of lamivudine via enzymatic dynamic kinetic resolution. Chem. Comm. 2013, 49, 10376. 

Zhang, Y.; Hu, L.; Ramström, O. Double Parallel Dynamic resolution through lipase-catalyzed asymmetric transformation. Chem. Comm. 2013, 49, 1805. 

Hu, L; Lan, P; Song, Q; Huang, Z; Sun, P; Zhuo, C; Wang, Y; Xiao, S; Chen, WM. Synthesis and antibacterial activity of C-12 pyrazolinyl spiro ketolides. Eur. J. Med. Chem., 2010, 45, 5943. 

Wang, Y-T‡ ; Hu, L‡ ; Chen W-M; Hu A-X; Song, Q-L; Guan D. Synthesis and antibacterial activities of (9S)-3-O-descladinose-6-O-methyl-3-oxo-12-(Δ2- pyrazolinyl)-12-dehydroxy-21-demethyl-9-dihydro-erythromycin A. Lett. Org. Chem., 2009,6, 306. ‡ 共同第一作者 

 

欢迎热爱药物化学的同学报考本人硕士研究生。