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金国范 资格教授

研究专业:药物化学,材料化学,有机金属化学

 

教育与工作简历: 

 

2017.4-至今, 江苏大学, 药学院, 资格教授

2014.6-2017.2, 韩国圆光大学, 自然科技大学, 研究教授

2011.10-2014.4, 韩国高丽大学, 博士后(研究教授)

2009.7–2011.10,韩国 OCT(株)医药研究所,科研组长

2006.7–2009.7, 韩国圆光大学, 药物化学, 理学博士

2004.7–2006.6, 韩国圆光大学, 药物化学, 理学硕士

2000.9–2004.6, 延边大学, 药学, 药学学士

 

研究方向:

1.癌症及肿瘤药物的设计合成与研发:主要包括BNCT 新型抗癌药                             物的设计,ODS治疗骨质疏松症新型药物研发,HIF-1 新型抑制抗癌药物的研发.

2.有机发光材料(Orgainc Light Emitting Diodides,OLED)      设计合成与研发:(ETL, HTL, EML and R, G, B dopant materials).

 

代表性论文:

1.Fan, Jin Guo; Kim, Mi Jin; Nguyen, Quynh Pham Bao; Braveenth, Ramanaskanda; Ko, Haye Min; Han, Ji-Hun; Kim, Gyeong Woo; Kwon, Jang Hyuk; Chai, Kyu Yun. Synthesis and Characterization of Carbazole Core-​based Small Molecular-​Hole-​transporting Materials for Red Phosphorescent OLEDs. Bull. Korean Chem. Soc. 2016.37 (10).

2.So-Yoen Kim,Yang-Jin Cho,Guo Fan Jin,Won-Sik Han,Ho-Jin Son,Dae Won Cho ,Sang Ook Kang.  Intriguing emission properties of triphenylamine-carborane systems. Physical Chemistry Chemical Physics.  2015. 05 17 (24).

3.So-Yoen KimAh-Rang LeeGuo Fan JinYang-Jin ChoHo-Jin Son*Won-Sik Han*,  SangOok Kang. Electronic Alteration on Oligothiophenes by o-Carborane: Electron Acceptor Character of o-Carborane in Oligothiophene Frameworks with Dicyano-Vinyl End-On Group.The Journal of OrganicChemistry.  2015. 80 9 (4573).

4.Guo Fan Jin,  Yang Jin Cho,  Jong-DaeLee,   Il-Hwan Suh, Dae Won Cho,Sang Ook Kang.BODIPY functionalized o-carborane dyads for low-energy photosensitization. Dalton Transactions.  2015. 44 (2780).

5.Guo Fan Jin,  Jo-Hyun Hwang,   Jong-DaeLee,  Kyung-Ryang Wee,   Il-Hwan SuhSang OokKang. Three-Dimensional -Electron Acceptor, Tri-Phenyl-o-Carborane, Bearing a Rigid Conformation with End-On Phenyl Units.  Chem.Com.  2013. 08.49 (9398)

6.Chai-Ho Lee, Guo Fan Jin,  Hyun Wha Lim, EunHye Yang, Jong-Dae Lee, HiroyukiNakamura, HyunSeungBan,SangOok Kang.  Facile synthesis of 4-substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides.  Heteroatom Chemistry.  2011. 01. 22 (192).

7.Guo Fan Jin, Chai-Ho Lee, jung Gun JoungJong-Dae LeeHyunSeungBanHiroyukiNakamuraJung-Keun ChoSang Ook Kang.New types of potential BNCT agents, o-carboranylaminoalcohols. Tetrahedron Letters. 2009. 03. 50 (2960).

8.Guo Fan Jin, Chai-Ho Lee, Ji Ho Yoon, Sun Hee Kim, Jong-Dae Lee, Hiroyuki Nakamura, Sang Ook Kang. Triazinyl architecture on bifunctionalcarboranyl templates for the production of potential neutron capture therapy agents: synthesis and characterization of 1,3,5-triazinylcarborane derivatives. Synthesis.2008. 04.8 (1193).

9.Guo Fan Jin, Chai-Ho Lee, Hyo-Suk Kim, Hiroyuki Nakamura, Jong-Dae Lee.  Synthesis and characterization of o-carboranylthiolate substituted 1,3,5-triazines. Bull. Korean Chem. Soc. 2008. 03. 29 (697).

10.Chai Ho Lee, Guo Fan Jin, Hyo Suk Kim, Hiroyuki Nakamura,YongseogChung, Jong Dae Lee .  Preparation of boronated heterocyclic compounds using intramolecular cyclization reaction.  Bull. Korean Chem. Soc. 2008. 02.29 (357).

11.Guo Fan Jin, Chai Ho Lee , Ji Ho Yoon, Young Ju Jung, Jong Dae Lee, Sung dong Cho,HiroyukiNakamuraSang Ook Kang. Synthesis and characterization of polar functional group substituted mono- and bis-(o-carboranyl)-1,3,5-triazine derivatives. Tetrahedron Letters. 2008. 01. 49 (159).

 

授权国内外专利:

 

  1. JIN,GUOFAN; Yoon, Ji Ho; Park, HyeonGyu; Jung, YeongJu; Kim, SeonHui; Kang, Sang Uk; Yoo, Ho Seong; Lee, Jong Dae; Lee, Chae Ho. Synthesis of 1,3,5-triazin-4-yl-dicarba-closo-dodecaborane derivative for use in anticancer agent for boron-neutron capture radiotherapy. KRXXA7  KR  2008077801  A  20080826.
  2. Lee, Chae Ho; Kang, Sang Uk; Chun, GiJeong; JIN,GUOFAN. Synthesis of (o-carboranyl)-1,3,5-triazine derivatives and pharmaceutical drug composition containing them. KRXXA7  KR  2008015209  A  20080219.
  3. JIN,GUOFAN; Yoon, Ji Ho; Jung, YeongJu; Kang, Sang Uk; Lee, Jong Dae; Lee, Chae Ho. 1,3,5-triazinylthiocarborane derivatives, their isomers and pharmaceutically acceptable salts, pharmaceutical composition containing the same and preparation method thereof.KRXXA7  KR  2009016794  A  20090218.
  4. Kim, Se-won, Kim, Jung Ho Kim, Se-nyum, Kang, Dae-pil, Han, Youn Ho, Jin, Guo Fan, Jung, Dong-sik Park, Sung-ho, Kim, Ji Min Zheng, Jh. α-Aryl-β-methoxyacrylate derivatives as HIF inhibitor and method for the preparation thereof. WO 2011132967 A2 20111027.
  5. 金国范 ; 金峰; 郑兵; 王凯,一种邻碳硼烷苯酚衍生物及其制备方法和应用.中国, 201610325461 .5.
  6. 金国范 ; 金峰; 王凯; 张艳; 张慧; 李柳斌,一种利用邻苯二甲酰亚胺制备双氟磺酰亚胺锂盐的方法,中国, 201610287182 .4.
  7. 金国范 ; 金峰; 王凯; 张艳; 张慧; 李柳斌. 一种利用芳香甲基叠氮制备双氟磺酰亚胺锂盐的方法,中国, 201610286982 .4.
  8. 金峰 ; 王凯; 金国范; 金英兰,邻碳硼烷衍生物、其制备方法和应用及制备该邻碳硼烷衍生物的中间体,中国, 201610286687 .9.
  9. 金国范 ; 金峰; 王凯, 一种双氟磺酰亚胺锂盐的制备方法.中国,201610195308 .5.
  10. 金国范;金峰;王凯;张艳;张慧;李柳斌,一种利用联氨制备双氟磺酰亚胺锂盐的方法,201610282164.7. 
  11. 金国范;金峰;王凯;张艳;张慧;李柳斌,一种利用羟基氨制备双氟磺酰亚胺锂盐的方法,201610287270.4.