谢萌

江苏大学药学院 副教授 硕士生导师

受教育及研究工作经历

2004.09-2008.06，苏州大学，药学院，药学，学士

2008.09-2013.06，浙江大学，药学院，药剂学，博士

2013.06-2016.06，江苏大学，药学院，药剂系，讲师

2016.06-至今，江苏大学，药学院，药剂系，副教授

（2018.03-2019.04，美国哥伦比亚大学，访问学者）

研究方向

功能化纳米生物材料的制备及靶向药物递送

阿尔兹海默症多靶点治疗

承担项目

[1] 中国博士后基金, 基于黑色g-C₃N₄的"双解聚-双清除"阿尔兹海默病光控自靶向治疗系统, 2021-2023, 主持

[2] 江苏省自然科学基金面上项目, 二维TMDs的生物伪装及成像引导下肿瘤精准治疗, 2020-2023, 主持

[3] 国家自然科学基金青年基金, 石墨烯基光控仿生递药体系的构建及其在肝癌多模式治疗中的应用, 2016-2018, 主持

[4] 中国博士后基金, 石墨烯/脂质光热响应性仿生药物载体的设计及性能评价, 2014-2016, 主持

个人荣誉

2024年 指导学生获得全国大学生生命科学竞赛（创新创业类）二等奖（国A）

2022年 指导学生获得全国大学生生命科学竞赛（创新创业类）一等奖（国A）

2022年 指导学位论文获评江苏大学2022年度优秀硕士学位论文

2021年 指导学生获得江苏省研究生药学类学术创新论坛论文一等奖

2022年 江苏大学第十一届教学竞赛高级职称组二等奖

2019年 江苏大学第四届双语及全英语教学竞赛三等奖

2021-2023年 连续三年获评江苏大学优秀学业导师

2017年 江苏大学“青年英才培育计划”优秀青年骨干教师培养人选

科研成果

（一）2018年之后论文清单

第一作者

[1] Meng Xie*, Pengkun Ye, Ruixin Zhao, Mei Yang. Magnetic WS₂ nanosheets functionalized by biomimetic lipids with enhanced dispersibility for combined photothermal and chemotherapy therapy. J. Drug Deliv. Sci. Tec. 2024, 86, 104744.

[2] Meng Xie*, Tongtong Deng, Jiaqian Li, Haijun Shen*. The camouflage of graphene oxide by red blood cell membrane with high dispersibility for cancer chemotherapy. J. Colloid Interf. Sci., 2021, 591, 290-299.

[3] Meng Xie*, Jiaqian Li, Na Yang, Mei Yang. Modification of magnetic molybdenum disulfide by chitosan/carboxymethylcellulose with enhanced dispersibility for targeted photothermal-/chemotherapy of cancer, J. Mater. Chem. B, 2021, 9, 1833-1845.

[4] Meng Xie, Pengkun Ye, Ruixin Zhao, Mei Yang. Magnetic WS₂ nanosheets functionalized by biomimetic lipids with enhanced dispersibility for combined photothermal and chemotherapy therapy. J. Drug Deliv. Sci. Tec. 2023, 86, 104744.

[5] Meng Xie, Duidui Wang, Liquan Jing, Wei Wei, Yuanguo Xu^⁎, Hui Xu, Huaming Li⁎, Jimin Xie. Preparation of magnetically recoverable and Z-scheme BaFe12O19/AgBr composite for degradation of 2-Mercaptobenzothiazole and Methyl orange under visible light. Appl. Surf. Sci. 2020, 521, 146343.

[6] Meng Xie*, Mei Yang, Xuan Sun, Na Yang, Tongtong Deng, Yeping Li, Haijun Shen*. WS₂ nanosheets functionalized by biomimetic lipids with enhanced dispersibility for photothermal and chemo combination therapy. J. Mater. Chem. B, 2020, 8, 2331-2342.

[7] Meng Xie*, Na Yang, Jiaxi Cheng, Mei Yang, Tongtong Deng, Yeping Li, Chunlai Feng*. Layered MoS₂ nanosheets modified by biomimetic phospholipids: Enhanced stability and its synergistic treatment of cancer with chemo-photothermal therapy. Colloids Surf B, 2020, 187, 110631.

[8] Meng Xie*, Feng Zhang, Houping Peng, Yanan Zhang, Yeping Li, Yuanguo Xu, Jimin Xie*, Layer-by-layer modification of magnetic graphene oxide by chitosan and sodium alginate with enhanced dispersibility for targeted drug delivery and photothermal therapy. Colloids Surf., B, 2019, 176, 462–470.

[9] Meng Xie, Feng Zhang, Lijiao Liu, Yanan Zhang, Yeping Li, Huaming Li*, Jimin Xie*. Surface modification of graphene oxide nanosheets by protamine sulfate/sodium alginate for anti-cancer drug delivery application. Appl. Surf. Sci., 2018, 440, 853–860.

[10] Zhenhua Xie^#, Yuanguo Xu^#, Meng Xie^#, Xiaobo Chen, Ji Hoon Lee, Eli Stavitski, Shyam Kattel, Jingguang G. Chen. Reactions of CO₂ and ethane enable CO bond insertion for production of C₃ oxygenates. Nat. Commun., 2020, 11, 1887.

[11] 谢萌, 杨眉, 杨娜, 等. 磁性二硫化钨的层层自组装修饰: 光热-化疗协同抗肿瘤.江苏大学学报(医学版)，2020, 30(3): 185–191．

通讯作者

[1] Jichun Liu, Mingyuan Chi, Lianxin Li, Yuewen Zhang, Meng Xie*. Erythrocyte membrane coated with nitrogen-doped quantum dots and polydopamine composite nano-system combined with photothermal treatment of Alzheimer's disease, J. Colloid Interf. Sci., 2024, 663:856-868

[2] Xiating Qi, Lianxin Li, Pengkun Ye, Meng Xie*. Macrophage Membrane-Modified MoS₂ Quantum Dots as a Nanodrug for Combined Multi-Targeting of Alzheimer's Disease, Advanced Healthcare Materials, 2024, 13: 2023211

[3] Mingyuan Chi, Jichun Liu, Lianxin Li, Yuewen Zhang, Meng Xie*. CeO₂ In Situ Growth on Red Blood Cell Membranes: CQD Coatingand Multipathway Alzheimer’s Disease Therapy under NIR. ACS Appl. Mater. Interfaces 2024, 16, 35898−35911.

[4] Mingyuan Chi, Jichun Liu, Lianxin Li, Yuewen Zhang, Meng Xie*. In-situ growth of CeO₂ on biofilms: Innovative nanoparticles for photothermal therapy & multi-pronged attack on Alzheimer’s disease. Colloids Surf., B 2024, 238, 113887

[5] Pengkun Ye, Lei Li, Xiating Qi, Mingyuan Chi, Jichun Liu, Meng Xie*. Macrophage membrane-encapsulated nitrogen-doped carbon quantum dot nanosystem for targeted treatment of Alzheimer’s disease: Regulating metal ion homeostasis and photothermal removal of β-amyloid. J. Colloid Interf. Sci., 2023, 650, 1749–1761.

[6] Xiating Qi, Pengkun Ye, Meng Xie*. MoS₂ quantum dots based on lipid drug delivery system for combined therapy against Alzheimer’s disease. J. Drug Deliv. Sci. Tec. 2023, 82, 104324.

[7] Jiaqian Li, Xiating Qi, Pengkun Ye, Mei Yang, Meng Xie*. Construction of WS₂/Au-lipid drug delivery system for multiple combined therapy of tumor. Drug Deliv. Sci. Tec. 2023, 76, 103747.

[8] Jia-Qian Li, Rui-Xin Zhao, Feng-Mei Yang, Xia-Ting Qi, Peng-Kun Ye, Meng Xie*. An erythrocyte membrane-camouflaged biomimetic nanoplatform for enhanced chemo-photothermal therapy of breast cancer. J. Mater. Chem. B, 2022, 10, 2047.

[9] Jiaqian Li, Na Yang, Mei Yang, Chao Lu*, Meng Xie*. Development of a magnetic MoS₂ system camouflaged by lipid for chemo/ phototherapy of cancer. Colloids Surf., B 2022, 213,112389.

[10] Feng Zhang, Meng Xie*, Yongwei Zhao, Yanan Zhang, Mei Yang, Na Yang, Tongtong Deng, Mingmei Zhang, Jimin Xie*, Chitosan and dextran stabilized GO-iron oxide nanosheets with high dispersibility for chemotherapy and photothermal ablation. Ceram. Int., 2019, 45, 5996–6003.

（二）授权专利

[1] 招瑞欣, 谢萌. 层状WS₂/Au@肿瘤细胞膜复合材料的制备方法及其应用, 2022-04-19, 中国, ZL 2022 1 0407111.9

[2] 谢萌, 张峰, 徐远国, 杨眉, 杨娜, 张雅楠. 一种磁性氧化石墨烯-壳聚糖/葡聚糖复合物的制备方法及应用, 2020-05-05, 中国, ZL 201711173539.7

[3] 谢萌, 张雅楠, 徐远国, 杨娜, 杨眉, 张峰. 一种氧化石墨烯-脂质纳米复合材料的制备方法及应用, 2020-06-09, 中国, ZL 201711178589.4

[4] 谢萌, 杨眉, 徐远国, 张雅楠, 杨娜, 张峰. 一种脂质修饰磁性氧化石墨烯复合材料的制备方法及应用, 2020-07-31, 中国, ZL 201711178607.9

[5] 谢萌, 刘彩虹, 徐远国, 张雅楠, 张峰, 雷海琳, 杨娜. 一种氧化石墨烯-鱼精蛋白/海藻酸钠复合物的制备方法及应用, 2020-01-24,中国, ZL 201710227407.1

联系方式

办公室：江苏大学药学院2213室

E-mail：xiemeng@ujs.edu.cn

手机号：15240280282