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谢萌

信息来源: 发布日期:2020-07-18

 


 谢萌

江苏大学药学院 副教授,硕士生导师

受教育及研究工作经历

2004.09-2008.06,苏州大学,药学院,药学,学士

2008.09-2013.06,浙江大学,药学院,药剂学,博士

2013.06-2016.06,江苏大学,药学院,药剂系,讲师

2016.06-至今,江苏大学,药学院,药剂系,副教授

2018.03-2019.04,美国哥伦比亚大学,访问学者)

研究方向

功能化纳米生物材料的制备及靶向药物递送

阿尔兹海默症及炎症疾病多靶点治疗

承担项目

[1] 镇江市科技计划社会发展面上项目,基于蒲公英的阿尔茨海默症鼻腔递送纳米药物设计及协同调控机理,2025-2027,主持

[2] 中国博士后基金, 基于黑色g-C3N4"双解聚-双清除"阿尔兹海默病光控自靶向治疗系统, 2021-2023, 主持

[3] 江苏省自然科学基金面上项目, 二维TMDs的生物伪装及成像引导下肿瘤精准治疗, 2020-2023, 主持

[4] 国家自然科学基金青年基金, 石墨烯基光控仿生递药体系的构建及其在肝癌多模式治疗中的应用, 2016-2018, 主持

[5] 中国博士后基金, 石墨烯/脂质光热响应性仿生药物载体的设计及性能评价, 2014-2016, 主持

个人荣誉

2024 指导学生获得全国大学生生命科学竞赛(创新创业类)等奖(国A

2022年 指导学生获得全国大学生生命科学竞赛(创新创业类)一等奖(国A

2025 指导学生获得全国大学生生命科学竞赛(创新创业类)等奖(国A

2022年 指导学位论文获评江苏大学20222025年度优秀硕士学位论文

2021年 指导学生获得江苏省研究生药学类学术创新论坛论文一等奖

2022年 江苏大学第十一届教学竞赛高级职称组二等奖

2019年 江苏大学第四届双语及全英语教学竞赛三等奖

2021-2024 连续多年获评江苏大学优秀学业导师

2017 江苏大学青年英才培育计划优秀青年骨干教师培养人选

科研成果

(一)2018年之后论文清单

第一作者

[1] Meng Xie*, Pengkun Ye, Ruixin Zhao, Mei Yang. Magnetic WS2 nanosheets functionalized by biomimetic lipids with enhanced dispersibility for combined photothermal and chemotherapy therapy. J. Drug Deliv. Sci. Tec. 2024, 86, 104744.

[2] Meng Xie*, Tongtong Deng, Jiaqian Li, Haijun Shen*. The camouflage of graphene oxide by red blood cell membrane with high dispersibility for cancer chemotherapy. J. Colloid Interf. Sci., 2021, 591, 290-299.

[3] Meng Xie*, Jiaqian Li, Na Yang, Mei Yang. Modification of magnetic molybdenum disulfide by chitosan/carboxymethylcellulose with enhanced dispersibility for targeted photothermal-/chemotherapy of cancer, J. Mater. Chem. B, 2021, 9, 1833-1845.

[4] Meng Xie, Pengkun Ye, Ruixin Zhao, Mei Yang. Magnetic WS2 nanosheets functionalized by biomimetic lipids with enhanced dispersibility for combined photothermal and chemotherapy therapy.  J. Drug Deliv. Sci. Tec. 2023, 86, 104744.

[5] Meng Xie, Duidui Wang, Liquan Jing, Wei Wei, Yuanguo Xu, Hui Xu, Huaming Li⁎, Jimin Xie. Preparation of magnetically recoverable and Z-scheme BaFe12O19/AgBr composite for degradation of 2-Mercaptobenzothiazole and Methyl orange under visible light. Appl. Surf. Sci. 2020, 521, 146343.

[6] Meng Xie*, Mei Yang, Xuan Sun, Na Yang, Tongtong Deng, Yeping Li, Haijun Shen*. WS2 nanosheets functionalized by biomimetic lipids with enhanced dispersibility for photothermal and chemo combination therapy. J. Mater. Chem. B, 2020, 8, 2331-2342. 

[7] Meng Xie*, Na Yang, Jiaxi Cheng, Mei Yang, Tongtong Deng, Yeping Li, Chunlai Feng*. Layered MoS2 nanosheets modified by biomimetic phospholipids: Enhanced stability and its synergistic treatment of cancer with chemo-photothermal therapy. Colloids Surf B, 2020, 187, 110631.

[8] Meng Xie*, Feng Zhang, Houping Peng, Yanan Zhang, Yeping Li, Yuanguo Xu, Jimin Xie*, Layer-by-layer modification of magnetic graphene oxide by chitosan and sodium alginate with enhanced dispersibility for targeted drug delivery and photothermal therapy. Colloids Surf., B, 2019, 176, 462–470.

[9] Meng Xie, Feng Zhang, Lijiao Liu, Yanan Zhang, Yeping Li, Huaming Li*, Jimin Xie*. Surface modification of graphene oxide nanosheets by protamine sulfate/sodium alginate for anti-cancer drug delivery application. Appl. Surf. Sci., 2018, 440, 853–860.

[10] Zhenhua Xie#, Yuanguo Xu#, Meng Xie#, Xiaobo Chen, Ji Hoon Lee, Eli Stavitski, Shyam Kattel, Jingguang G. Chen. Reactions of CO2 and ethane enable CO bond insertion for production of C3 oxygenates. Nat. Commun., 2020, 11, 1887.

[11] 谢萌, 杨眉, 杨娜, . 磁性二硫化钨的层层自组装修饰: 光热-化疗协同抗肿瘤.江苏大学学报(医学版)2020, 30(3): 185191

通讯作者

[1] Wang Yan, Li Lianxin, Zhou Puyang, Gan Yu, Liu Weipeng, Wang Yiwen, Deng Yilin, Li Hongping; Xie Meng*, Xu Yuanguo. Aeration-Free Photo-Fenton-Like Reaction Mediated by Heterojunction Photocatalyst toward Efficient Degradation of Organic Pollutants, Angew. Chem. Int. Ed. 2025, 64, e202419680.

[2] Yuewen Zhang, Yancheng Hong, Fengmei Yang, Yujiao Yan, Ruixin Zhao, Meng Xie*. TGN peptide and erythrocyte membrane dual-modified selenium-doped carbon quantum dots for multifaceted treatment of Alzheimers's disease. Chem. Eng. J., 2025, 514, 163340

[3] Lianxin Li, Yu Xiong, Yuewen Zhang, Yujiao Yan, Ruixin Zhao, Fengmei Yang, Meng Xie*. Biofilm-camouflaged Prussian blue synergistic mitochondrial mass enhancement for Alzheimer's disease based on Cu2+ chelation and photothermal therapy. J. Controlled Release,2024, 375, 269-284.

[4] Yujiao Yan, Yutong Chen, Fengmei Yang, Ruixin Zhao, Die Tian, Liran Deng, Meng Xie*. In-situ engineering of a covalent organic framework-based biomimetic nanoplatform for multi-target therapy of Alzheimer’s disease, Biomaterials Advances, 2026, 182, 214728

[5] Fengmei Yang, Yutong Chen, Yujiao Yan, Ruixin Zhao, Liran Deng, Die Tian, Meng Xie*, Biomimetic red blood cell membran-coated cerium metal-organic framework for multi-target synergistic therapy of Alzheimers disease, Colloids and Surfaces B: Biointerfaces, 2026, 262, 115464

[6] Ruixin Zhao,   Mengrong Guo,   Fengmei Yang,   Yujiao Yan,   Die Tian,   Liran Deng,   Qi Wang*  and  Meng Xie*. A Microglia membrane biomimetic platinum-based MOF-loaded quercetin nanodrug delivery system for the treatment of Alzheimer's disease. Journal of Materials Chemistry B, 2026, DOI: 10.1039/D6TB00201C

[7] Lianxin Li, Jiayang Zhang, Yuewen Zhang, Ruixin Zhao , Fengmei Yang, Yujiao Yan, Qi Wang*, Meng Xie*. Biofilm-modified Prussian blue improves memory function in late-stage Alzheimer’s disease mice with triple therapy. Inter. J. Pharm. 2025, 670,125112

[8] Xiating Qi, Lianxin Li, Pengkun Ye, Meng Xie*. Macrophage Membrane-Modified MoS2 Quantum Dots as a Nanodrug for Combined Multi-Targeting of Alzheimer's Disease, Adv. Healthc. Mater., 2024, 13: 2023211

[9] Mingyuan Chi, Jichun Liu, Lianxin Li, Yuewen Zhang, and Meng Xie*. CeO2 In Situ Growth on Red Blood Cell Membranes: CQD Coating and Multipathway Alzheimers Disease Therapy under NIR.  ACS Appl. Mater. Interfaces 2024, 16, 3589835911

[10] Mingyuan Chi , Jichun Liu, Lianxin Li, Yuewen Zhang, Meng Xie. In-situ growth of CeO2 on biofilms: Innovative nanoparticles for photothermal therapy & multi-pronged attack on Alzheimers disease. Colloids and Surfaces B: Biointerfaces 2024, 238, 113887.

[11] Jichun Liu, Mingyuan Chi, Lianxin Li, Yuewen Zhang, Meng Xie*. Erythrocyte membrane coated with nitrogen-doped quantum dots and polydopamine composite nano-system combined with photothermal treatment of Alzheimer's disease, J. Colloid Interf. Sci., 2024, 663:856-868

[12] Xiating Qi, Lianxin Li, Pengkun Ye, Meng Xie*. Macrophage Membrane-Modified MoS2 Quantum Dots as a Nanodrug for Combined Multi-Targeting of Alzheimer's Disease, Advanced Healthcare Materials, 2024, 13: 2023211

[13] Mingyuan Chi, Jichun Liu, Lianxin Li, Yuewen Zhang, Meng Xie*. CeO2 In Situ Growth on Red Blood Cell Membranes: CQD Coatingand Multipathway Alzheimers Disease Therapy under NIR. ACS Appl. Mater. Interfaces 2024, 16, 3589835911.

[14] Mingyuan Chi, Jichun Liu, Lianxin Li, Yuewen Zhang, Meng Xie*. In-situ growth of CeO2 on biofilms: Innovative nanoparticles for photothermal therapy & multi-pronged attack on Alzheimers disease. Colloids Surf., B 2024, 238, 113887

[15] Pengkun Ye, Lei Li, Xiating Qi, Mingyuan Chi, Jichun Liu, Meng Xie*. Macrophage membrane-encapsulated nitrogen-doped carbon quantum dot nanosystem for targeted treatment of Alzheimer’s disease: Regulating metal ion homeostasis and photothermal removal of β-amyloid. J. Colloid Interf. Sci., 2023, 650, 1749–1761.

[16] Xiating Qi, Pengkun Ye, Meng Xie*. MoS2 quantum dots based on lipid drug delivery system for combined therapy against Alzheimer’s disease. J. Drug Deliv. Sci. Tec. 2023, 82, 104324.

[17] Jiaqian Li, Xiating Qi, Pengkun Ye, Mei Yang, Meng Xie*. Construction of WS2/Au-lipid drug delivery system for multiple combined therapy of tumor. Drug Deliv. Sci. Tec. 2023, 76, 103747.

[18] Jia-Qian Li, Rui-Xin Zhao, Feng-Mei Yang, Xia-Ting Qi, Peng-Kun Ye, Meng Xie*. An erythrocyte membrane-camouflaged biomimetic nanoplatform for enhanced chemo-photothermal therapy of breast cancer. J. Mater. Chem. B, 2022, 10, 2047.

[19] Jiaqian Li, Na Yang, Mei Yang, Chao Lu*, Meng Xie*. Development of a magnetic MoS2 system camouflaged by lipid for chemo/ phototherapy of cancer. Colloids Surf., B 2022, 213,112389.

[20] Feng Zhang, Meng Xie*, Yongwei Zhao, Yanan Zhang, Mei Yang, Na Yang, Tongtong Deng, Mingmei Zhang, Jimin Xie*, Chitosan and dextran stabilized GO-iron oxide nanosheets with high dispersibility for chemotherapy and photothermal ablation. Ceram. Int., 2019, 45, 5996–6003.

 

(二)授权专利

[1] 招瑞欣, 谢萌. 层状WS2/Au@肿瘤细胞膜复合材料的制备方法及其应用, 2022-04-19, 中国, ZL 2022 1 0407111.9

[2] 谢萌, 张峰, 徐远国, 杨眉, 杨娜, 张雅楠. 一种磁性氧化石墨烯-壳聚糖/葡聚糖复合物的制备方法及应用, 2020-05-05, 中国, ZL 201711173539.7

[3] 谢萌, 张雅楠, 徐远国, 杨娜, 杨眉, 张峰. 一种氧化石墨烯-脂质纳米复合材料的制备方法及应用, 2020-06-09, 中国, ZL 201711178589.4

[4] 谢萌, 杨眉, 徐远国, 张雅楠, 杨娜, 张峰. 一种脂质修饰磁性氧化石墨烯复合材料的制备方法及应用, 2020-07-31, 中国, ZL 201711178607.9

[5] 谢萌, 刘彩虹, 徐远国, 张雅楠, 张峰, 雷海琳, 杨娜. 一种氧化石墨烯-鱼精蛋白/海藻酸钠复合物的制备方法及应用, 2020-01-24,中国, ZL 201710227407.1

 

联系方式

办公室:江苏大学药学院2213

E-mailxiemeng@ujs.edu.cn

手机号15240280282

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