潘承谦，男，1992年生，浙江湖州人，江苏大学药学院资格副教授。从事植物、微生物来源天然活性物质的提取分离、结构鉴定及功效研究，擅长物质分离纯化及复杂天然产物结构解析。

【联系方式】

Email：cqpan@ujs.edu.cn

地址：江苏大学药学院 制药工程系2413

【工作经历】

2023-08至今，江苏大学，药学院，资格副教授

2022-01至2023-07，浙江养生堂天然药物研究所有限公司，植化研究员

2020-10至2021-09，上海翰森生物医药科技有限公司，分析研究员

【教育经历】

2017-04至2020-09，京都大学，博士

2014-09至2017-03，浙江大学，硕士

2010-09至2014-06，浙江大学，学士

【研究方向】

1. 植物与微生物的新颖活性次级代谢产物发现

2. 基于复合培养方法的微生物潜在次级代谢产物研究

3. 活性天然产物的结构改造与构效关系研究

【主持科研及人才项目】

1. 江苏大学高级人才科研启动基金，2024至2026，在研，主持

【发表论文】

1. Pan C#, Ikeda H#, Minote M, Tokuda T, Kuranaga T, Taniguchi T, Shinzato N, Onaka H, Kakeya H. Amoxetamide A, a new anoikis inducer, produced by combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis. J. Antibiot. 2024, 77, 66-70.(#为共同第一作者)

2. Pan C, Kuranaga T, Cao X, Suzuki T, Dohmae N, Shinzato N, Onaka H, Kakeya H. Amycolapeptins A and B, Cyclic nonadepsipeptides produced by combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis. J. Org. Chem. 2021, 86, 1843-1849.

3. Pan C, Kuranaga T, Kakeya H. Application of the highly sensitive labeling reagent to the structural confirmation of readily isomerizable peptides. J. Nat. Med. 2021, 75, 339-343.

4. Pan C, Kuranaga T, Kakeya H. Total synthesis of thioamycolamide A via a biomimetic route. Org. Biomol. Chem. 2020, 18, 8366-8370.

5. Pan C, Kuranaga T, Liu C, Lu S, Shinzato N, Kakeya H. Thioamycolamides A-E, sulfur-containing cycliclipopeptides produced by the rare actinomycete Amycolatopsis sp. Org. Lett. 2020, 22, 3014-3017.

6. Pan C, Shi Y, Auckloo B N, Chen C T A, Chen X, Wu X, Wu B. Four verrucosidin derivatives isolated from the hydrothermal vent sulfur-derived fungus Penicillium sp. Y-50-10. Chem. Nat. Compd. 2018, 54, 253-256.

7. Pan C, Shi Y, Auckloo B N, Hassan S S, Akhter N, Wang K, Ye Y, Chen C T A, Tao X, Wu B. Isolation and antibiotic screening of fungi from a hydrothermal vent site and characterization of secondary metabolites from a Penicillium isolate. Mar. Biotechnol. 2017, 19, 469-479.

8. Pan C, Shi Y, Chen X, Chen C T A, Tao X, Wu B. New compounds from a hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4. Org. Biomol. Chem. 2017, 15, 1155-1163.

9. Pan C, Lu J, Wu B, Wu L, Li B. Effect of monomer structure on crystallization and glass transition of flexible copolyesters. J. Polym. Environ. 2017, 25, 1051-1061.

10. Pan C, Shi Y, Auckloo B N, Chen X, Chen C T A, Tao X, Wu B. An Unusual conformational isomer of verrucosidin backbone from a hydrothermal vent fungus, Penicillium sp. Y-50-10. Mar. Drugs 2016, 14, 156.

合作作者：

1. Kanoh N, Terashima R, Nishiyama H, Terajima Y, Nagasawa S, Sasano Y, Iwabuchi Y, Saito H, Egoshi S, Dodo K, Sodeoka M, Pan C, Ikeuchi Y, Nishimura S, Kakeya H. Design, synthesis, and antifungal activity of 16,17-dihydroheronamide C and ent-heronamide C. J. Org. Chem. 2021, 86, 16249-16258.

2. Kuranaga T, Minote M, Morimoto R, Pan C, Ogawa H, Kakeya H. Highly sensitive labeling reagents for scarce natural products. ACS Chem. Biol. 2020, 15, 2499-2506.

3. Shi Y, Pan C, Cen S, Fu L, Cao X, Wang H, Wang K, Wu B. Comparative metabolomics reveals defence-related modification of citrinin by Penicillium citrinum within a synthetic Penicillium-Pseudomonas community. Environ. Microbiol. 2019, 21, 496-510.

4. Akhter N, Pan C, Liu Y, Shi Y, Wu B. Isolation and structure determination of a new indene derivative from endophytic fungus Aspergillus flavipes Y-62. Nat. Prod. Res. 2019, 33, 2939-2944.

5. Auckloo BN, Pan C, Akhter A, Wu B, Wu X, He S. Stress-driven Discovery of Novel Cryptic Antibiotics from a Marine Fungus Penicillium sp. BB1122. Front. Microbiol. 2017, 8, 1450.

6. Shi Y, Pan C, Chen C-T A, Wu B. Synthetic multispecies microbial communities reveals shifts in secondary metabolism and facilitates cryptic natural product discovery. Environ. Microbiol. 2017, 19, 3606-3618.

7. Shi Y, Pan C, Auckloo BN, Chen X, Chen C-T A, Wang K, Wu X, Ye Y, Wu B. Stress-driven discovery of a cryptic antibiotic produced by Streptomyces sp. WU20 from Kueishantao hydrothermal vent with an integrated metabolomics strategy. Appl. Microbiol. Biotech. 2017, 101, 1395-1408.