一、基本信息

姓名：谢萌

通讯地址：江苏省镇江市学府路301号 江苏大学药学院（邮编：212013）

电子邮件：xiemeng@ujs.edu.cn

二、个人简介

谢萌，女，江苏大学药学院副教授、硕士生导师，长期从事纳米药物递送及生物传感研究，主持国家级/省部级科研项目4项，连续3年入选爱思唯尔全球前2%顶尖科学家（2024-2026）。在Angewandte Chemie-International Edition, Nature Communications, Chem. Eng. J. , J. Control Release, J. Colloid Interf. Sci., 等国内外权威期刊发表论文40余篇。

三、教育经历

•2008.09-2013.06，浙江大学，药剂学专业，博士学位

•2004.09-2008.06，苏州大学，药学院，药学专业，学士学位

四、工作经历

•2916.6—至今 江苏大学药学院，副教授、硕士生导师

•2013.06-2016.06，江苏大学药学院，讲师

•（2018.03-2019.04，美国哥伦比亚大学，访问学者）

五、研究方向

1.功能化纳米生物材料的制备及靶向药物递送

2.阿尔茨海默症及炎症疾病多靶点治疗

3.生物传感

六、科研成果

6.1 科研项目

•2025.09-2027.06｜镇江市科技计划社会发展面上项目“基于蒲公英的阿尔茨海默症鼻腔递送纳米药物设计及协同调控机理”（项目编号：SH2025034）｜镇江市科技局｜主持

•2021.09-2023.06｜中国博士后基金面上项目“基于黑色g-C₃N₄的"双解聚-双清除"阿尔兹海默病光控自靶向治疗系统”（项目编号：2021M701502）｜中国博士后基金委员会｜主持

•2020.09-2023.06｜江苏省自然科学基金面上项目“二维TMDs的生物伪装及成像引导下肿瘤精准治疗”（项目编号：BK20201419）｜江苏省科技厅｜主持

•2016.01-2018.12｜国家自然科学基金青年基金项目“石墨烯基光控仿生递药体系的构建及其在肝癌多模式治疗中的应用”（项目编号：21506079）｜国家自然科学基金委员会｜主持

•2014.09-2016.06｜中国博士后基金面上项目“石墨烯/脂质光热响应性仿生药物载体的设计及性能评价”（项目编号：2014M560399）｜中国博士后基金委员会｜主持

6.2 学术论文

[1] Wang Yan, Li Lianxin, Zhou Puyang, Gan Yu, Liu Weipeng, Wang Yiwen, Deng Yilin, Li Hongping; Xie Meng*, Xu Yuanguo. Aeration-Free Photo-Fenton-Like Reaction Mediated by Heterojunction Photocatalyst toward Efficient Degradation of Organic Pollutants, Angew. Chem. Int. Ed. 2025, 64, e202419680.

[2] Yuewen Zhang, Yancheng Hong, Fengmei Yang, Yujiao Yan, Ruixin Zhao, Meng Xie*. TGN peptide and erythrocyte membrane dual-modified selenium-doped carbon quantum dots for multifaceted treatment of Alzheimers's disease. Chem. Eng. J., 2025, 514, 163340

[3] Lianxin Li, Yu Xiong, Yuewen Zhang, Yujiao Yan, Ruixin Zhao, Fengmei Yang, Meng Xie*. Biofilm-camouflaged Prussian blue synergistic mitochondrial mass enhancement for Alzheimer's disease based on Cu²⁺ chelation and photothermal therapy. J. Controlled Release, 2024, 375, 269-284.

[4] Yujiao Yan, Yutong Chen, Fengmei Yang, Ruixin Zhao, Die Tian, Liran Deng, Meng Xie*. In-situ engineering of a covalent organic framework-based biomimetic nanoplatform for multi-target therapy of Alzheimer’s disease, Biomaterials Advances, 2026, 182, 214728

[5] Fengmei Yang, Yutong Chen, Yujiao Yan, Ruixin Zhao, Liran Deng, Die Tian, Meng Xie*, Biomimetic red blood cell membran-coated cerium metal-organic framework for multi-target synergistic therapy of Alzheimer’s disease, Colloids and Surfaces B: Biointerfaces, 2026, 262, 115464

[6] Ruixin Zhao, Mengrong Guo, Fengmei Yang, Yujiao Yan, Die Tian, Liran Deng, Qi Wang* and Meng Xie*. A Microglia membrane biomimetic platinum-based MOF-loaded quercetin nanodrug delivery system for the treatment of Alzheimer's disease. Journal of Materials Chemistry B, 2026, 14, 6034-6049

[7] Lianxin Li, Jiayang Zhang, Yuewen Zhang, Ruixin Zhao , Fengmei Yang, Yujiao Yan, Qi Wang*, Meng Xie*. Biofilm-modified Prussian blue improves memory function in late-stage Alzheimer’s disease mice with triple therapy. Inter. J. Pharm. 2025, 670,125112

[8] Xiating Qi, Lianxin Li, Pengkun Ye, Meng Xie*. Macrophage Membrane-Modified MoS₂ Quantum Dots as a Nanodrug for Combined Multi-Targeting of Alzheimer's Disease, Adv. Healthc. Mater., 2024, 13: 2023211

[9] Mingyuan Chi, Jichun Liu, Lianxin Li, Yuewen Zhang, and Meng Xie*. CeO₂ In Situ Growth on Red Blood Cell Membranes: CQD Coating and Multipathway Alzheimer’s Disease Therapy under NIR. ACS Appl. Mater. Interfaces 2024, 16, 35898−35911

[10] Mingyuan Chi , Jichun Liu, Lianxin Li, Yuewen Zhang, Meng Xie. In-situ growth of CeO₂ on biofilms: Innovative nanoparticles for photothermal therapy & multi-pronged attack on Alzheimer’s disease. Colloids and Surfaces B: Biointerfaces 2024, 238, 113887.

[11] Jichun Liu, Mingyuan Chi, Lianxin Li, Yuewen Zhang, Meng Xie*. Erythrocyte membrane coated with nitrogen-doped quantum dots and polydopamine composite nano-system combined with photothermal treatment of Alzheimer's disease, J. Colloid Interf. Sci., 2024, 663:856-868

[12] Pengkun Ye, Lei Li, Xiating Qi, Mingyuan Chi, Jichun Liu, Meng Xie*. Macrophage membrane-encapsulated nitrogen-doped carbon quantum dot nanosystem for targeted treatment of Alzheimer’s disease: Regulating metal ion homeostasis and photothermal removal of β-amyloid. J. Colloid Interf. Sci., 2023, 650, 1749–1761.

[13] Xiating Qi, Pengkun Ye, Meng Xie*. MoS₂ quantum dots based on lipid drug delivery system for combined therapy against Alzheimer’s disease. J. Drug Deliv. Sci. Tec. 2023, 82, 104324.

[14] Jiaqian Li, Xiating Qi, Pengkun Ye, Mei Yang, Meng Xie*. Construction of WS₂/Au-lipid drug delivery system for multiple combined therapy of tumor. J. Drug Deliv. Sci. Tec. 2023, 76, 103747.

[15] Jia-Qian Li, Rui-Xin Zhao, Feng-Mei Yang, Xia-Ting Qi, Peng-Kun Ye, Meng Xie*. An erythrocyte membrane-camouflaged biomimetic nanoplatform for enhanced chemo-photothermal therapy of breast cancer. J. Mater. Chem. B, 2022, 10, 2047.

[16] Jiaqian Li, Na Yang, Mei Yang, Chao Lu*, Meng Xie*. Development of a magnetic MoS₂ system camouflaged by lipid for chemo/ phototherapy of cancer. Colloids Surf., B 2022, 213,112389.

6.3 专利与软件著作权

[1] 招瑞欣, 谢萌. 层状WS₂/Au@肿瘤细胞膜复合材料的制备方法及其应用, 2022-04-19, 中国, ZL 2022 1 0407111.9

[2] 谢萌, 张峰, 徐远国, 杨眉, 杨娜, 张雅楠. 一种磁性氧化石墨烯-壳聚糖/葡聚糖复合物的制备方法及应用, 2020-05-05, 中国, ZL 201711173539.7

[3] 谢萌, 张雅楠, 徐远国, 杨娜, 杨眉, 张峰. 一种氧化石墨烯-脂质纳米复合材料的制备方法及应用, 2020-06-09, 中国, ZL 201711178589.4

[4] 谢萌, 杨眉, 徐远国, 张雅楠, 杨娜, 张峰. 一种脂质修饰磁性氧化石墨烯复合材料的制备方法及应用, 2020-07-31, 中国, ZL 201711178607.9

[5] 谢萌, 刘彩虹, 徐远国, 张雅楠, 张峰, 雷海琳, 杨娜. 一种氧化石墨烯-鱼精蛋白/海藻酸钠复合物的制备方法及应用, 2020-01-24,中国, ZL 201710227407.1