一、基本信息

姓名：杨永青

通讯地址：江苏省镇江市学府路301号 江苏大学药学院（邮编：212013）

电子邮件：yqy@ujs.edu.cn

二、个人简介

杨永青，女，江苏大学药学院副教授、硕士生导师，长期从事光驱动的药物合成反应及生物活性分子合成的研究。

三、教育经历

•2001.09—2006.07 中国科学院上海有机所，有机化学专业，博士学位

•1997.09—2001.07 山东师范大学，化学教育专业，学士学位

四、工作经历

•2021.07—至今 江苏大学药学院，副教授、硕士生导师

•2012.12—2021.06 江苏大学药学院，讲师

•2010.11—2012.04 上海睿智化学研究有限公司，高级研究员

•2009.01—2010.09 英国剑桥大学化学系C. Abell教授研究组，博士后研究人员

•2007.01—2009.01 英国诺丁汉大学化学院N. R. Thomas教授研究组，玛丽·居里研究学者

•2006.07—2006.11 上海晟康生物医药有限公司，研究员

五、研究方向

1.药物分子的结构修饰与工艺开发，

2.可见光驱动的化学反应在药物合成中的应用

3.新型保护基的设计与合成。

六、科研成果

6.1 科研项目

•2016.01—2019.12｜面上项目“发展基于抑制P110alpha[E545K]-IRS1相互作用的新型潜在抗癌药物” （项目编号：21572080）｜国家自然科学基金委员会｜参与（排名第三）

•2013.01—2015.01｜高级人才启动基金项目“合成新型1，2，4-三嗪-5-酮衍生物及其抗癌活性的研究”（项目编号：14JDG018）｜江苏大学｜主持

6.2 学术论文

1.Yong-Qing Yang*, Jinhao Cui, Zheng Lu* and Ximing Xu*. On-column reduction of aldehyde with diMe-Imd-BH3: simultaneous reaction and purification by flash chromatography [J] ARKIVOC, 2026, DOI: 10.24820/ark.5550190.p012.636 (SCI四区，IF=0.6)

2.Yong-Qing Yang*, Wenhua Ruan, Zheng Lu*, Xiaoqian Li, Ximing Xu*. The Improved Synthesis of 2-[Dimethylphenylsilyl]ethanol (DMPSE-OH) and Its Utility in Carboxyl Protection[J]. Synlett, 2026, 37(08): 977-980. (SCI四区，IF=1.5)

3.Zhiyong Wang, Dan Peng*, Zheng Lu, Yong-Qing Yang*. Study on hydrosilylation of alkenes bearing an adamantyl pendant[J]. 2025, DOI: 10.24820/ark.5550190.p012.388. (SCI四区，IF=0.6)

4.Yong-Qing Yang*, Jialu Liu, Zheng Lu*, Ximing Xu*. Green Light-Driven Reduction of Methylenemalononitriles with Formate as a Reductant Without a Thiol Hydrogen-Atom-Transfer Catalyst[J] SYNTHESIS-STUTTGART, 2025, 57 (19): 2861-2868. (SCI四区，IF=2.2)

5.Yong-Qing Yang*, Yue Xu, Junjie Yuan, Jialu Liu, Jie Yin, Zheng Lu*, Ximing Xu*. meso -Hydroxylmethyl-1,3,5,7-tetramethylBODIPY: A Visible-Light Photoremovable Protective Group for Carboxyl Groups[J] SYNTHESIS-STUTTGART 2024, 56 (23): 3646-3652. (SCI四区，IF=2.2)

6.Yue Xu, Jing Shu, Ying Wang, Zheng Lu*, Yong-Qing Yang*, XimingXu*. Constructing 4-hydroxythiazole-5-carboxamide building blocks in one pot [J] ARKIVOC, 2023, DOI:10.24820/ark.5550190.p012.046. (SCI四区，IF=0.6)

7.Zheng Lu*, Yue Xu, Ze Wen, Changhong Xie, Chengyue Xie, Mengqian Yu, Lingyun Gao, Yong-Qing Yang*, Ximing Xu*. A Visible-Light-Driven Approach to Free Alcohol from Esters of Quinone Propionic Acid[J]. SYNTHESIS-STUTTGART, 2023, 55(3):473-480. (SCI四区，IF=2.2)

8.Yong-Qing Yang, Zheng Lu*, Jinming Chen, Ximing Xu*.Desymmetrizing Hantzsch pyridines via promoter-free benzylic C-H functionalization[J]. ARKIVOC, 2020, DOI: 10.24820/ark.5550190.p011.115. (SCI四区，IF=0.6)

9.Yong-Qing Yang, Zheng Lu*, Ximing Xu*. Phenacyl Xanthates: A Photoremovable Protecting Group for Alcohols under Visible Light[J] Asian Journal of Organic Chemistry, 2019, 8(12), 2192-2195. (SCI三区，IF=2.3)

10.Zheng Lu, Yong-Qing Yang*. Catalyst-Free Photodriven Reduction of -Haloketones with Hantzsch Ester [J] SYNTHESIS-STUTTGART, 2019, 51(2):508-515. (SCI四区，IF=2.2)

11.Zheng Lu, Yong-Qing Yang*, Weixiang Xiong. Preparation of 1,3-Thiazolidine-2-thiones by Using Potassium Ethylxanthate as a Carbon Disulfide Surrogate[J]. Synlett, 2019, 30(6), 713-716. (SCI四区，IF=1.5)

12.Zheng Lu, Yong-Qing Yang*, Jin-Hui Li, Jun-Nan Wei, Yi-Zhu Wang. Convenient approach to chiral 4-monosubstituted 1,3-oxazolidine-2-thiones[J]. Synthetic Communications, 2017, 47(23): 2215-2219. (SCI三区，IF=1.8)

13.Yong-Qing Yang, Meng-Nan Zhu, Zheng Lu*, Li-Ting Chen, Jing Su. Claisen-Schmidt Condensation Involved with C-C Bond Cleavage[J] Chines Journal of Organic Chemistry, 2016, 36(5): 1073-1079. (SCI三区，IF=1.6)

14.Yong-Qing Yang*. Synthesis and absolute configuration of natural 8-hydroxyl-9-angeloyloxythymol[J]. Synthetic communications, 2016, 46(11):971-976. (SCI三区，IF=1.8)

15.Yong-Qing Yang*. Evidence against the structure proposed for a natural phenylethanol isolated from mangrove Avicennia marina[J]. Synthetic Communications, 2016, 46(15), 1263-1267. (SCI三区，IF=1.8)

16.Zheng Lu, Yong-Qing Yang*, Hong-Xia, Li. Photoinduced Aromatization of Dihydropyridines[J] SYNTHESIS-STUTTGART, 2016, 48(23): 4221-4227. (SCI四区，IF=2.2)

17.Yong-Qing Yang, Meng-Chen Ji, Zheng Lu*, Mao Jiang, Wei-Wei Huang, Xue-Zhi He.Facile access to α,β-dehydroalanine and α,β-dehydroamino butyric acid derivatives from DL-serines and threonines[J] Synthetic Communications, 2016, 46(11): 977-982. (SCI三区，IF=1.8)

18.Yong-Qing Yang* Synthesis and disproof of the structure proposed for the tetrahydrofuranol isolated from Michelia compressa var. lanyuensis (Magnoliaceae)[J] Natural Product Research, 2016, 30(14): 1628-1632. (SCI三区，IF=1.8)

19.Yong-Qing Yang, Zheng Lu*. A Convenient Heterogeneous Reduction of Knoevenagel Product by Hantzsch Ester and Its Development into Reductive Alkylation of Malononitrile[J]. Chines Journal of Chemistry, 2014, 32(7), 650-653. (SCI一区，IF=4.7)