一、基本信息

姓名：华中一

所属系部：中药学与药学系

通讯地址：江苏省镇江市学府路301号 江苏大学药学院（邮编：212013）

电子邮件：hzy@ujs.edu.cn

二、个人简介

华中一，男，中药学博士，江苏大学药学院讲师。主要从事中药基原核酸数据资源建设、道地药材品质形成机制解析及中药专属性分子标记开发，并开展中医药大数据整合与AI信息挖掘研究。在Horticulture Research、Plant Biotechnology Journal、Molecular Ecology Resources、Plant Communications等期刊发表学术论文。主持江苏省基础研究计划青年基金项目等项目3项，参与相关项目1项。现任中华中医药学会中药鉴定分会青年委员、中国中西医结合学会分子生药学专业委员会青年委员。

三、教育经历

2018.09—2024.06｜中国中医科学院｜中药学｜博士学位

2014.09—2018.06｜南京中医药大学｜中药制药｜学士学位

四、工作经历

2025.06—至今｜江苏大学药学院｜讲师

五、研究方向

1.中药分子鉴定

2.道地药材形成机制研究

3.中医药大数据整合与AI信息挖掘

六、科研成果

6.1 科研项目

1.2026.07—2026.09｜丹参基因组质量提升｜横向项目｜10万元｜主持。

2.2026—2029｜SDR基因演化格局与功能分化驱动苏薄荷化学型形成机制｜江苏省基础研究计划青年基金项目｜20万元｜主持。

3.2026—2028｜薄荷醇脱氢酶基因家族分化参与薄荷道地药材相关化学型形成的分子机制｜名贵中药资源可持续利用能力建设项目｜20万元｜主持。

4.2024—2027｜中医药生命组学大数据底座建设｜名贵中药资源可持续利用能力建设项目｜450万元｜参与。

6.2 学术论文——代表性期刊论文

1.Teng, X., Hua, Z., Hao, S., Zhang, M., Xie, Y., Zhu, X., Huang, L., Yuan, Y. The orchid Gastrodia-derived extracellular vesicles deliver miR535 to suppress a fungal effector and facilitate symbiosis with Armillaria[J]. Plant Communications, 2026: 102149. DOI: 10.1016/j.xplc.2026.102149. (Online ahead of print, 2026.10)

2.Hua, Z., Li, L., Chen, Y., Cao, Y., Liu, W., Teng, X., et al., Yuan, Y. Chromosome-level genome assembly and population genomics unveil strigolactone-regulated growth adaptation in the mycoheterotrophic orchid Gastrodia elata[J]. Horticulture Research, 13(7), 2026, uhag099.

3.Hua, Z.*, Teng, X.*, Huang, J., Zhou, J., Zhao, Y., Huang, L.†, Yuan, Y.† The Armillaria response to Gastrodia elata is partially mediated by strigolactone-induced changes in reactive oxygen species[J]. Microbiological Research, 278, 2024, 127536.

4.Zhang, Y.*, Liu, T.*, Nan, T., Hua, Z.†, Zhao, Y., Yuan, Y.† Characteristics and functions of volatile organic compounds in the tripartite symbiotic system of Gastrodia elata-Armillaria gallica-Rahnella aceris HPDA25[J]. Plant Signaling & Behavior, 19(1), 2024, 2399426.

5.Hua, Z.*, Jiang, C.*, Song, S.*, Tian, D.*, Chen, Z., Jin, Y., et al., Yuan, Y.† Accurate identification of taxon-specific molecular markers in plants based on DNA signature sequence[J]. Molecular Ecology Resources, 23(1), 2023, 106-117.

6.Han, P., Hua, Z., Zhao, Y., Huang, L.†, Yuan, Y.† PuCRZ1, an C2H2 transcription factor from Polyporus umbellatus, positively regulates mycelium response to osmotic stress[J]. Frontiers in Microbiology, 14, 2023, 1131605.

7.Jiao, H., Hua, Z., Zhou, J., Hu, J., Zhao, Y., Wang, Y., et al., Huang, L.† Genome-wide analysis of Panax MADS-box genes reveals role of PgMADS41 and PgMADS44 in modulation of root development and ginsenoside synthesis[J]. International Journal of Biological Macromolecules, 233, 2023, 123648.

8.Zhou, T., Xu, K.†, Zhao, F., Liu, W., Li, L., Hua, Z., Zhou, X. itol. toolkit accelerates working with iTOL (Interactive Tree of Life) by an automated generation of annotation files[J]. Bioinformatics, 39(6), 2023, btad339.

9.Li, C., Jin, L., Zhang, C., Li, S., Zhou, T., Hua, Z., et al., Liu, J.†. Destabilized microbial networks with distinct performances of abundant and rare biospheres in maintaining networks under increasing salinity stress[J]. iMeta, 2(1), 2023, e79.

10.Hua, Z.*, Tian, D.*, Jiang, C.*, Song, S., Chen, Z., Zhao, Y., et al., Yuan, Y.† Towards comprehensive integration and curation of chloroplast genomes[J]. Plant Biotechnology Journal, 20(12), 2022, 2239-2241.

11.Hua, Z.*, Liu, T.*, Han, P., Zhou, J., Zhao, Y., Huang, L., Yuan, Y.† Isolation, genomic characterization, and mushroom growth-promoting effect of the first fungus-derived Rhizobium [J]. Frontiers in Microbiology, 13, 2022, 947687.

12.Yu, M.*, Hua, Z.*, Liao, P. R., Zheng, H., Jin, Y., Peng, H. S., et al., Yuan, Y.† Increasing expression of PnGAP and PnEXPA4 provides insights into the enlargement of Panax notoginseng root size from Qing dynasty to cultivation era[J]. Frontiers in Plant Science, 13, 2022, 878796.

13.Liu, T.*, Hua, Z.*, Han, P., Zhao, Y., Zhou, J., Jin, Y., et al., Yuan, Y.† Mycorrhizosphere Bacteria, Rahnella sp. HPDA25, 2022, promotes the growth of Armillaria gallica and its parasitic host Gastrodia elata. [J] Frontiers in Microbiology, 13, 842893.

6.3 专利与软件著作权

专利

1.袁媛;华中一;赵玉洋;黄璐琦. 快速筛选高纯合度天麻的方法及其所用引物组合物: CN114990252B[P]. 2026.02.

2.袁媛, 刘天睿, 华中一, 南铁贵, 赵玉洋, 周骏辉, 李晓琳, 黄璐琦. 一种与天麻优形优质相关的单倍型分子标记及其应用:CN113736904B[P]. 2023.10.

3.袁媛, 华中一, 蒋超, 黄璐琦. 一种使用DNA特征序列鉴定植物的方法: CN113322340B[P]. 2022.09.

软件著作权

1.中国中医科学院中药研究所, 华中一, 袁媛. DNA 序列特征性片段鉴定软件[简称:IdenDSS] V2.0: 2023SR0348944. 2023.03.

2.中国中医科学院中药研究所, 华中一, 袁媛. 药用动植物种质资源重测序分析流程生成器软件[简称:MGRAG] V1.0: 2022SR0597293. 2022.05.

3.中国中医科学院中药研究所, 华中一, 袁媛. 微卫星标记工具箱软件[简称:IdenSSR] V1.0: 2022SR0597299. 2022.05.

4.中国中医科学院中药研究所. DNA 序列特征性片段鉴定软件[简称:IdenDSS] V1.0: 2021SR0112964. 2021.01.