一、基本信息

姓名：李小兰通讯地址：江苏省镇江市学府路301号 江苏大学药学院（邮编：212013）

办公电话：0511-85038451

电子邮件：lixiaolan@ujs.edu.cn

二、个人简介

李小兰，女，江苏大学药学院讲师、硕士生导师。长期从事天然活性物质的生物合成、稳定化及益生功能方向的研究，主持省部级科研项目1项，参与国家级/省部级科研项目2项。在Compr Rev Food Sci Food Saf (IF 14.80)、 Bioresour Technol (IF 11.40)、Int J Biol Macromol (IF 8.50)、 Ultrason Sonochem (IF 8.40)、 J Agr Food Chem (IF 6.10)、Mol Nutr Food Res (IF 6.58)、J Sci Food Agric (3.50)、 J Anim Sci (IF 3.34)等国内外期刊发表论文24篇，申请发明专利5件。担任《Food & Medicine Homology》、《Journal of future food》期刊青年编委，以及《Food Science and Human Wellness》、《Food & Medicine Homology》、《Journal of future food》、《食品科学》等期刊审稿人。

三、教育经历

•2019.09—2023.06 江苏大学，食品科学与工程专业，博士学位

•2012.09—2015.06 南昌大学，营养与食品卫生学专业，硕士学位

•2008.09—2012.06 甘肃农业大学，生物技术专业，学士学位

四、工作经历

•2023.08—至今 江苏大学药学院，讲师、硕士生导师

五、研究方向

1.天然活性物质的生物合成与制造；

2.天然活性物质的稳定化研究及应用；

3.天然生物活性物质的益生功能；

六、科研成果

6.1 科研项目

•2024.07—2027.06｜江苏省自然科学基金青年项目｜BK20240849｜主持

•2026.01—2029.12｜国家自然科学基金面上项目｜32572499｜参与（排名第二）

•2020.01—2024.12｜国家重点研发计划子课题｜2021YFA0910401｜参与（排名第七）

6.2 学术论文

1.Li XL, Liang YT, Zhang GY, Wan JQ, Yu YF, Hua ZY, Zhang ZH, Qi XH, Ouyang Z*. L-xylulose, a new versatile rare sugar: recent biosynthetic advances and challenges [J]. Food Research International, 2026, 235, 119625. (SCI一区, IF=8.8)

2.Li XL, Zhang ZH, Li C, Fan YL, Hou MH, Wang SC, Zhang ZK, Gao XL. Mechanisms for enhancing ethanol tolerance of Saccharomyces cerevisiae through nano-selenium supplementation during Chinese rice wine brewing [J]. Journal of the Science of Food and Agriculture, 2025, 105, 6064–6071. (SCI三区, IF=3.50)

3.Zhang ZH, Wang HY, Han XY, Huang X, Zeng QH, Li XL^*, Gao XL^*. The effect of different wall materials on the physicochemical properties and antioxidant activity of pomegranate peel polyphenols (PPP) microcapsules [J]. International Journal of Biological Macromolecules, 2025, 298, 139958. (SCI一区, IF=8.50)

4.Pan CQ, Ni HH, Li ZY, Yang KT, Hassan SSU^*, Li XL^*, Kakeya H^*. Recent advances in bioactive natural products from plant fruits: Structures, activities, and future prospects [J]. Plant Foods for Human Nutrition, 2025, 80, 191. (SCI二区, IF=3.60)

5.Li XL, Zabed HM, Yun JH, Zhang GY, Zhao M, Zhang CS, Ouyang Z, Li J, Qi XH^*. Sustainable bio-manufacturing of D-arabitol through combinatorial engineering of Zygosaccharomyces rouxii, bioprocess optimization and downstream separation [J]. Bioresource Technology, 2024, 393, 130162. (SCI一区, IF=11.40)

6.Li XL, Zhang YF, Yun JH, Zhang GY, Zhao M, Zabed HM, Qi XH^*. High-level production of D-arabitol by Zygosaccharomyces rouxii from glucose: metabolic engineering and process optimization [J]. Bioresource Technology, 2023, 367, 128251. (SCI一区, IF=11.40)

7.Li XL, Jian H, Yun JH, Zhang GY, Zhang YF, Zhao M, Zabed HM, Qi XH^*. D-arabitol ameliorates obesity and metabolic disorders via the gut microbiota-SCFAs-WAT browning axis [J]. Journal of Agricultural and Food Chemistry, 2023, 71, 522-534. (SCI一区, IF=6.10)

8.Li XL, Zhang ZH, Qiao JQ, Qu WJ, Wang MS, Gao XL, Zhang CS^*, Brennan CS. Qi XH^*. Improvement of betalains stability extracted from red dragon fruit peel by ultrasound-assisted microencapsulation with maltodextrin [J]. Ultrasonics Sonochemistry, 2022, 82, 105897. (SCI一区, IF=8.40)

9.Li XL, Zhang ZH, Qi XH, Li L, Zhu J^*, Brennan CS, Yan JK^*. Application of nonthermal processing technologies in extracting and modifying polysaccharides: A critical review [J]. Comprehensive Reviews in Food Science and Food Safety, 2021, 20, 4367–4389. (SCI一区, IF=14.80)

10.Li XL, Zhang ZH, Zabed HM, Yun JH, Zhang GY, Qi XH^*. An insight into the roles of dietary tryptophan and its metabolites in intestinal inflammation and inflammatory bowel disease [J]. Molecular Nutrition & Food Research, 2021, 65, 2000461. (SCI二区, IF=6.58)

6.3 专利与软件著作权

•李小兰, 梁亚婷, 欧阳臻, 齐向辉, 万晶琼, 于一凡. 一种基于两步酶法控制构型反转高效制备L-木酮糖的方法及其应用: CN202411778662.1 [P]. 2024-12-05.

•齐向辉, 李小兰, 赵梅, 张存胜, 陈自卫. 一种高产D-阿拉伯糖醇的鲁氏酵母工程菌及其构建方法和应用: CN202311429854.7 [P]. 2023-10-31