一、基本信息

姓名：潘承谦

通讯地址：江苏省镇江市学府路301号 江苏大学药学院（邮编：212013）

电子邮件：cqpan@ujs.edu.cn

二、个人简介

潘承谦，男，1992年生，浙江长兴人，民革党员，江苏大学药学院资格副教授，硕士生导师，江苏省双创博士。长期从事微生物来源天然产物化学研究。主持国家级/省部级科研项目2项，参与1项。在Org Lett、J Org Chem、J Nat Prod、Eur J Med Chem等国内外权威期刊发表论文20余篇。担任SCI期刊《Frontiers in Marine Science》、《Letters in Organic Chemistry》专刊编辑等学术职务。

三、教育经历

•2017.4—2020.9 日本京都大学，医药创新信息科学专业，博士学位

•2014.9—2017.3 浙江大学，海洋科学专业，硕士学位

•2010.9—2014.6 浙江大学，化学工程与工艺专业，学士学位

四、工作经历

•2023.8—至今 江苏大学药学院，资格副教授、硕士生导师

•2022.1—2023.7 浙江养生堂天然药物研究所有限公司，植化研究员

•2020.10—2021.9 上海翰森生物医药科技有限公司，分析研究员

五、研究方向

1.微生物的新颖活性次级代谢产物发现

2.基于复合培养方法的微生物潜在次级代谢产物研究

3.活性天然产物的结构改造与构效关系研究

六、科研成果

6.1 科研项目

•2025.1—2027.12｜国家自然科学基金青年项目（项目编号：82404465）｜国家自然科学基金委员会｜主持

•2025.7—2027.6｜江苏省双创博士项目（项目编号：JSSCBS0623）｜江苏省科技厅｜主持

•2024.1—2026.12｜江苏大学高级人才科研启动基金（项目编号：5501290012）｜江苏大学｜主持

•2026.1—2029.12｜国家自然科学基金面上项目（项目编号：82574882）｜国家自然科学基金委员会｜参与

6.2 学术论文

21.Zou Y, Gong C, Pan C*. Neuroprotective effects of natural products: Innovative therapeutic strategies for preventing the progression of neurodegenerative diseases. Mini-Rev. Med. Chem. 2026

20.Pan C, Yang K, Li Z, et al. An overview of novel compounds from marine invertebrates: Sources, structures, and bioactivities. Curr. Med. Chem. 2026.

19.Pan C, Tang Z, Kakeya H. Mushroom-derived metabolites: A promising sourceof novel lead compounds for pharmaceutical and functional food applications. Med. Chem. Res. 2026.

18.Tang W, Hu L, Pan C*. Bioactive compounds from cyanobacteria: A mini review. Curr. Top. Med. Chem. 2026.

17.Pan C, Kurimura M, Taniguchi M, et al. Piperapeptins A and B, cyclic hexapeptides containing the rare amino acid piperazic acid, produced by a combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis. J. Nat. Prod. 2026

16.Pan C, Zhang L, Kuranaga T, et al. Combination of combined-culture of Amycolatopsis sp. with Tsukamurella pulmonis and GNPS molecular networking reveals novel sulfur-containing cyclic lipopeptides thioamycolamides F–I. J. Antibiot. 2026, 79(5): 293-300.

15.Pan C, Ni H, Li Z, et al. Recent advances in bioactive natural products from plant fruits: structures, activities, and future prospects. Plant Food Hum. Nutr. 2025, 80(4): 191.

14.Pan C, Kakeya H. Recent progress in chemistrty and bioactivity of novel enzyme inhibitors from natural products: a comprehensive review. Eur. J. Med. Chem. 2025, 289, 117481.

13.Pan C, Hassan S S, Ishaq M, et al. Marine actinomycetes: a hidden treasure trove for antibacterial discovery. Front. Mar. Sci. 2025, 12: 1558320.

12.Yi R, Shi Y, Cao X, Pan C*. Actinomycetes: treasure trove for discovering novel antibiotic candidates. Eur. J. Med. Chem. 2025, 117317.

11.Pan C#*, Hassan SS#, Muhammad I, Jin H*. Marine fungi as a goldmine for novel antibiotics: a 2024 perspective. Front. Mar. Sci. 2025. (#为共同第一作者)

10.Pan C#, Ikeda H#, Minote M, Tokuda T, Kuranaga T, Taniguchi T, Shinzato N, Onaka H, Kakeya H. Amoxetamide A, a new anoikis inducer, produced by combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis. J. Antibiot. 2024, 77, 66-70.(#为共同第一作者)

9.Pan C, Kuranaga T, Cao X, Suzuki T, Dohmae N, Shinzato N, Onaka H, Kakeya H. Amycolapeptins A and B, Cyclic nonadepsipeptides produced by combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis. J. Org. Chem. 2021, 86,1843-1849.

8.Pan C, Kuranaga T, Kakeya H. Application of the highly sensitive labeling reagent to the structural confirmation of readily isomerizable peptides. J. Nat. Med. 2021, 75, 339-343.

7.Pan C, Kuranaga T, Kakeya H. Total synthesis of thioamycolamide A via a biomimetic route. Org. Biomol. Chem. 2020, 18,8366-8370.

6.Pan C, Kuranaga T, Liu C, Lu S, Shinzato N, Kakeya H. Thioamycolamides A-E, sulfur-containing cycliclipopeptides produced by the rare actinomycete Amycolatopsis sp. Org. Lett. 2020, 22, 3014-3017.

5.Pan C, Shi Y, Auckloo B N, Chen C T A, Chen X, Wu X, Wu B. Four verrucosidin derivatives isolated from the hydrothermal vent sulfur-derived fungus Penicillium sp. Y-50-10. Chem. Nat. Compd. 2018, 54, 253-256.

4.Pan C, Shi Y, Auckloo B N, Hassan S S, Akhter N, Wang K, Ye Y, Chen C T A, Tao X, Wu B. Isolation and antibiotic screening of fungi from a hydrothermal vent site and characterization of secondary metabolites from a Penicillium isolate. Mar. Biotechnol. 2017, 19, 469-479.

3.Pan C, Shi Y, Chen X, Chen C T A, Tao X, Wu B. New compounds from a hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4. Org. Biomol. Chem. 2017, 15, 1155-1163.

2.Pan C, Lu J, Wu B, Wu L, Li B. Effect of monomer structure on crystallization and glass transition of flexible copolyesters. J. Polym. Environ. 2017, 25, 1051-1061.

1.Pan C, Shi Y, Auckloo B N, Chen X, Chen C T A, Tao X, Wu B. An Unusual conformational isomer of verrucosidin backbone from a hydrothermal vent fungus, Penicillium sp. Y-50-10. Mar. Drugs 2016, 14, 156.

合作作者：

10.Mao D, Lu S, Su X, Pan C, et al. Mannodaidzein, a rare daidzein mannoside isolated froma rare actinomycete Saccharothrix sp. JS2. Rec. Nat. Prod. 2025, 1: 12-12.

9.ul Hassan S S, Ahmad N, Rehman A, Pan C, et al. A cinderella story in antimicrobials: CDPDP’s perfect fit for multiple-pathway bacterial inhibition. Eur. J. Med. Chem. 2025: 117967.

8.Tokuda T, Kuranaga T, Minote M, Minote M, Ikeda H, Pan C, Kakeya H. Structural elucidation using highly sensitive labeling reagents and total synthesis of a new anoikis inducer amoxetamide A. Chem. Eur. J. 31, e202500357, 2025.

7.Kanoh N, Terashima R, Nishiyama H, Terajima Y, Nagasawa S, Sasano Y, Iwabuchi Y, Saito H, Egoshi S, Dodo K, Sodeoka M, Pan C, Ikeuchi Y, Nishimura S, Kakeya H. Design, synthesis, and antifungal activity of 16,17-dihydroheronamide C and ent-heronamide C. J. Org. Chem. 2021, 86, 16249-16258.

6.Kuranaga T, Minote M, Morimoto R, Pan C, Ogawa H, Kakeya H. Highly sensitive labeling reagents for scarce natural products. ACS Chem. Biol. 2020, 15, 2499-2506.

5. Shi Y, Pan C, Cen S, Fu L, Cao X, Wang H, Wang K, Wu B. Comparative metabolomics reveals defence-related modification of citrinin by Penicillium citrinum within a synthetic Penicillium-Pseudomonas community. Environ. Microbiol. 2019, 21, 496-510.

4.Akhter N, Pan C, Liu Y, Shi Y, Wu B. Isolation and structure determination of a new indene derivative from endophytic fungus Aspergillus flavipes Y-62. Nat. Prod. Res. 2019, 33, 2939-2944.

3.Auckloo BN, Pan C, Akhter A, Wu B, Wu X, He S. Stress-driven Discovery of Novel Cryptic Antibiotics from a Marine Fungus Penicillium sp. BB1122. Front. Microbiol. 2017, 8, 1450.

2.Shi Y, Pan C, Chen C-T A, Wu B. Synthetic multispecies microbial communities reveals shifts in secondary metabolism and facilitates cryptic natural product discovery. Environ. Microbiol. 2017, 19, 3606-3618.

1.Shi Y, Pan C, Auckloo BN, Chen X, Chen C-T A, Wang K, Wu X, Ye Y, Wu B. Stress-driven discovery of a cryptic antibiotic produced by Streptomyces sp. WU20 from Kueishantao hydrothermal vent with an integrated metabolomics strategy. Appl. Microbiol. Biotech. 2017, 101, 1395-1408.