Part 1 Basic Information
Name: Zhou Shengwang
Address: School of Pharmacy, Jiangsu University, No. 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China
Email: shengwangzhou@ujs.edu.cn
Part 2 Personal Profile
Dr. Zhou Shengwang is a Professor and Master's Supervisor at the School of Pharmacy, Jiangsu University, and a recipient of the Jiangsu Province Shuangchuang Doctor award. His research focuses on drug delivery systems, biomedical imaging, and recombinant protein therapeutics. He has led three national- and provincial-level research projects and published more than 20 papers in leading international journals, including Chemical Science, Chemical Engineering Journal, Biosensors and Bioelectronics, and Chemical Communications. He also serves as a peer reviewer for several international journals, including Advanced Functional Materials and the International Journal of Nanomedicine.
Part 3 Education
•2016.06–2020.08 Postdoctoral Research Fellow, Department of Biomedical Engineering, Northwestern University, USA
•2015.10–2016.05 Postdoctoral Research Fellow, College of Chemistry and Chemical Engineering, Hunan University, China
•2011.09–2015.09 Ph.D., College of Chemistry and Chemical Engineering, Nanjing University, China
Part 4 Work Experience
•2020.09–Present, Professor and Master's Supervisor, School of Pharmacy, Jiangsu University, China
Part 5 Research Interests
1.Development of biomacromolecule-gated mesoporous drug delivery systems with multiple stimuli-responsive controlled release properties.
2.Self-assembly of recombinant fusion proteins through geometrically defined architectures and the development of nanotherapeutics based on antibody-mimetic structures.
3.Design and synthesis of antibody–drug conjugates (ADCs).
4.Protein micropatterning on biomaterial surfaces and its applications in cell migration.
5.Synthesis of photoresponsive molecules and investigation of their covalent conjugation with recombinant proteins.
Part 6 Research Achievements
6.1 Research Projects
•2022.01–2025.12 | Principal Investigator, National Natural Science Foundation of China (NSFC) General Program: Multi-armed Anti-PD-L1 Gated Near-Infrared-Emitting Afterglow Mesoporous Silica Drug Delivery System for Combined Tumor Therapy and Multimodal Imaging (Grant No. 82172745), National Natural Science Foundation of China.
•2022.09–2023.08 | Principal Investigator, Jiangsu Province "Shuangchuang Doctor" Program (World-Renowned Universities Category) (Grant No. JSSCBS20210978).
•2016.05–2018.05 | Principal Investigator, General Program of the China Postdoctoral Science Foundation: Photoactivatable Reaction for Covalent Nanoscale Patterning of Multiple Proteins (Grant No. 2016M592420).
6.2 Publications
1.Xu, Tingyu; Wei, Jia; Zhang, Zihan; Xia, Haonan; Zhou, Shengwang*. Programmable crosslinking strategies for the rational design of engineered protein hydrogels [J]. Colloids and Surfaces B-biointerfaces, 2027, 269: 116115. （SCI一区，IF=5.9）
2.Bi, Jingli; Gao, Lingyun; Xu, Yufei; Tan, Zhenhai; Zhou, Shengwang*. Covalently engineered PQDs-fluorescent protein FRET probes for tumor imaging and diagnosis [J]. Biosensors and Bioelectronics, 2026, 297: 118381. （SCI一区，IF=11.8）
3.Gao, Lingyun; Xu, Yufei; Tan, Zhenhai; Bi, Jingli; Zhou, Shengwang*. Construction of anti-HER2 conjugated injectable hydrogel via protein crosslinking and gadolinium-tetraaza coordination for multimodal tumor theranostics [J]. Colloids and Surfaces B-biointerfaces, 2026, 264: 115667. （SCI一区，IF=5.9）
4.Tan, Zhenhai; Xu, Tingyu; Zhou, Shengwang*. Covalently Anti-HER2-Functionalized MOF for Targeted Chemotherapy and NIR-Activated Photothermal/Photodynamic Cancer Therapy [J]. ACS Applied Polymer Materials, 2026, 8(12): 9211-9222. (SCI二区，IF=5.2)
5.Han, Xu; Chen, Jia; Cheng, Zhihao; Zhou, Shengwang*. Design of an anti-PD-L1-mediated MOF nanodrug delivery system using terpyridine-metal coordination for tumor theranostics [J]. Chemical Communications, 2025, 61(7): 1407-1410. (SCI二区，IF=4.3)
6.Han, Xu; Chen, Jia; Zhao, Yangjing; Kang, Ruike; Wei, Yuan; Zhou, Shengwang*. Dual antibody-guided drug delivery systems using MOF-PQDs nanocomposites for precise tumor diagnosis and combination therapy [J]. Chemical Engineering Journal, 2025, 505: 159275. （SCI一区，IF=12.5）
7.Chen, Yue; Xu, Yufei; A, Sihan; Shen, Binbin; Zhou, Shengwang*. Anti-PD-L1 immobilization on Fe3O4 nanocluster-coated AuNR through terpyridine-gadolinium coordination for multimodal imaging and synergistic tumor therapy [J]. Colloids and Surfaces B-biointerfaces, 2025, 256: 115047. （SCI一区，IF=5.9）
8.Zhou, Shengwang*, Wei, Yuan. Kaleidoscope Megamolecules Synthesis and Application Using Self-assembly Technology [J]. Biotechnology Advances 2023, 65, 108147. （SCI一区，IF=14.1）
9.Chen, Yue; Feng, Honghong; Chen, Long; Zhou, Wenbin; Zhou, Shengwang*. Construction of homologous branched oligomer megamolecules based on linker-directed protein assembly [J]. Soft Matter 2024, 20(35), 6889-6893. （SCI二区，IF=2.9）
10.Feng, Honghong; Zhao, Yangjing; Li, Yeping; Qi, Xueyong; Shen, Song; Zhou, Shengwang*. ACS Applied Nano Materials 2023, 6(14), 13001-13012. （SCI二区，IF=5.8）
6.3 Patents and Software Copyrights
•Zhou, Shengwang, Zhao, Yangjing, Feng, Honghong. A Multi-Armed Anti-CD40 Antibody-Mediated Nanocarrier for Dual-Drug Delivery: Preparation Method and Applications [P]. China, Patent No. 202310866556.8, 2025-10-3.
•Zhou, Shengwang, Han, Xu, Zhao, Yangjing. An Anti-PD-L1 and Anti-HER2 Dual-Antibody-Guided Nanotherapeutic System: Preparation Method and Applications [P]. China, Patent No. 202411430799.8, 2024-10-14.
