Part 1 Basic Information

Name:Yuping Shen (Shen Yuping)

Address: School of Pharmacy, Jiangsu University, No. 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China

Email: syp131@ujs.edu.cn

Part 2 Personal Profile

Shen Yuping, female, Associate Professor and Master’s Supervisor at the School of Pharmacy, Jiangsu University. Her main research interests include biotransformation and enzyme-catalyzed preparation of bioactive components from traditional Chinese medicines, biomarker protein and DNA molecular identification of animal-derived medicinal materials, as well as screening and functional evaluation of bioactive natural products. She has presided over the General Program and Young Scientists Fund of the National Natural Science Foundation of China, together with multiple enterprise horizontal research projects, with total research funding of more than 2.5 million RMB received. As the first or corresponding author, she has published over 40 SCI-indexed papers, many of which were published in Chinese Academy of Sciences Q1 TOP journals including Int J Biol Macromol, J Pharm Anal, and Food Res Int. She has filed 7 national invention patents, among which 3 have been granted.

In teaching, she teaches the national first-class course Pharmaceutical Analysis A. She participated in compiling the English textbook PHARMACEUTICAL ANALYSIS, a concise textbook for international students studying in China. She undertakes teaching tasks for undergraduate and international student courses.

Part 3 Education

•2012.09–2019.09, Jiangsu University, Clinical Laboratory Diagnostics, Ph.D.

•2002.09–2005.06, Jiangsu University, Pharmacognosy, M.S.

•1998.09–2002.06, Jiangsu University, Pharmacy, B.S.

Part 4 Work Experience

•2014.07–Present, School of Pharmacy, Jiangsu University, Associate Professor

•2017.01–2018.01, School of Biological Sciences, Nanyang Technological University, Singapore, Visiting Scholar

•2007.08–2014.06, School of Pharmacy, Jiangsu University, Lecturer

•2002.09–2007.07, School of Pharmacy, Jiangsu University, Teaching Assistant

Part 5 Research Interests

1.Acquisition of bioactive components from traditional Chinese medicines, focusing on biotransformation and enzyme-catalyzed technology.

2.Screening, isolation, preparation and functional evaluation of bioactive natural products.

3.Key identification technologies for animal-derived medicinal materials, including signature protein and DNA molecular identification.

Part 6 Research Achievements

6.1 Research Projects

•2024.05–2025.12 | Enterprise-commissioned R&D Project “Development of Manufacturing Technology for Novel Healthy Foods Containing Medicinal and Edible Materials” (Project No. HX20240438) | Industry-university commissioned project | Principal Investigator

•2022.02–2022.12 | Enterprise-commissioned R&D Project “Development of Key Technologies for Quality Control of Five Tastes Chinese Herbal Decoction Pieces” (Project No. HX20220099) | Industry-university commissioned project | Principal Investigator

•2019.01–2022.12 | General Program of National Natural Science Foundation of China “Construction of a Novel and Efficient Enzymatic Hydrolysis System for Obtaining Bioactive Components from Traditional Chinese Medicines”(Grant No.81873196) | NSFC | Principal Investigator

•2014.01–2016.12 | Young Scientists Fund of National Natural Science Foundation of China “Study on Signature Proteins and Peptides in Animal-derived Medicinal Materials as Characteristic Identifiers by MALDI-TOF/TOF-MS”(Grant No.81303174) | NSFC | Principal Investigator

6.2 Publications

1.Zheng H X, Deng X L, Li T T, Xia G H, Yang H, Peng J S, Shen Y P. Mining anticoagulant peptides from Poecilobdella manillensis by peptidomics analysis[J]. Natural Products and Bioprospecting, 2026, 16(1): 24. ( SCI Q2, IF=5.8)

2.Chen J X, Jiayang Z M, Meng L Z, Zhu Y T, Qian S Y, Xia G H, Yang H, Shen Y P. Anti-aging effects of rare prosaikogenin F from microbial biotransformation of saikosaponin A[J]. Fitoterapia, 2026, 190:107174. ( SCI Q3, IF=2.9)

3.Xia G H, Li H X, Wang M J, Zhang L, Zhou C S, Shen Y P, Yang H. Bactericidal mechanisms of intense pulsed light against Salmonella Enteritidis on green Sichuan pepper[J]. Food Research International, 2025, 219:117042. ( SCI Q1, IF=8.0, TOP Journal )

4.Chen Y F, Wang L W, Guo Y A, Zhang M J, Xie H C, Xia G H, Xu L L, Yang H, Shen Y P. Preparation of isoquercitrin and rhamnose from readily accessible rutin by a highly specific recombinant α-L-rhamnosidase (r-Rha1)[J]. Natural Product Research, 2025, 39(9):2566-2571. ( SCI Q3, IF=1.6)

5.Tang L L, Shao J L, Zheng H X, Chen J X, Xia G H, Yang H, Yang Y Y, Shen Y P. Cleaner production of baicalein by novel high-temperature-little-acid hydrolysis of baicalin[J]. Green Chemistry Letters and Reviews, 2024, 17(1):2319698. ( SCI Q3, IF=6.6 )

6.Peng J S, Li Y, Deng X L, Lu M Y, Yang C B, Shen Y P, Xia G H, Yang H. Loop-Mediated Isothermal Amplification for On-Site Visual Identification of Leech Species[J]. Food Analytical Methods, 2024, 17(4):618-627. ( SCI Q3, IF=2.6 )

7.Lu Y, Luo Q L, Jia X B, Tam J P, Yang H, Shen Y P, Li X. Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and nanotechnology[J]. Journal of Pharmaceutical Analysis, 2023, 13(3):239-254. ( SCI Q1, IF=14.026 )

8.Wang L W, Yang C Y, Deng X L, Peng J S, Zhou J W, Xia G H, Zhou C S, Shen Y P, Yang H. A pH-sensitive intelligent packaging film harnessing Dioscorea zingiberensis starch and anthocyanin for meat freshness monitoring[J]. International Journal of Biological Macromolecules, 2023, 245:125485. ( SCI Q1, IF=8.2, TOP Journal )

9.Shen Y P, Zhou J W, Yang C Y, Chen Y F, Yang Y Y, Zhou C S, Wang L W, Xia G H, Yu X J, Yang H. Preparation and characterization of oregano essential oil-loaded Dioscorea zingiberensis starch film with antioxidant and antibacterial activity and its application in chicken preservation[J]. International Journal of Biological Macromolecules, 2022, 212:20-30. ( SCI Q1, IF=8.025, TOP Journal )

10.Zhang Y J, Yang R, Wang L W, Li Y, Han J, Yang Y Y, Zheng H X, Lu M Y, Shen Y P, Yang H. Purification and characterization of a novel thermostable anticoagulant protein from medicinal leech Whitmania pigra Whitman[J]. Journal of Ethnopharmacology, 2022, 288:114990. ( SCI Q2, IF=5.195 )

11.Shen Y P, Wang M, Zhou J W, Chen Y F, Wu M R, Yang Z Z, Yang C Y, Xia G H, Tam J P, Zhou C S, Yang H, Jia X B. Construction of Fe₃O₄@α-glucosidase magnetic nanoparticles for ligand fishing of α-glucosidase inhibitors from a natural tonic Epimedii Folium[J]. International Journal of Biological Macromolecules, 2020, 165: 1361-1372. ( SCI Q1, IF=5.162, TOP Journal )

12.Lin L, Zhang Y J, Li Y, Fu H Z, Hu J H, Zhou Y, Xu Y, Xia G H, Sun X X, Yang H, Shen Y P. Identification of signature proteins of processed Bombyx batryticatus by comparative proteomic analysis [J]. International Journal of Biological Macromolecules, 2020, 153: 289-296. ( SCI Q1, IF=5.162, TOP Journal )

6.3 Monographs and Textbooks

•Qi Xueyong (Chief Editor). EXPERIMENT OF PHARMACEUTICAL ANALYSIS [M]. Jiangsu: Jiangsu University Press, 2018, ISBN 978-7-5684-0884-4. (Associate Editor)

•Tong Shanshan, Yu Jiangnan (Chief Editors). PHARMACEUTICAL ANALYSIS [M]. Jiangsu: Jiangsu University Press, 2018, ISBN 978-7-5684-0946-9. (Contributor)

6.4 Patents and Software Copyrights

•Shen Y P, Yang H, Xia G H, Zhou C S, Wang H Y, Lu Y. A method for obtaining Baohuoside I by biphasic enzymatic hydrolysis: ZL 201611119179.8[P]. 2020-06-26.

•Yang H, Tang L L, Zhu Y T, Xie H C, Yang Y Y, Jing S L, Yang C Y, Zhang L, Chen Y F, Shen Y P, Xia G H. A method for extracting baicalein by low-acid hydrolysis in high-boiling-point solvent: ZL 202210640994.8[P]. 2024-09-27.

•Yang H, Yu P T, Shen Y P, Cai B C, Jiao Z Q, Chen L Q, Chen Y F, Lu B B. A set of specific primers for identification of Carapax Trionycis and its identification method: ZL 201711487466.9[P]. 2020-09-25.