Part 1 Basic Information

Name: Qingtong Yu

Address: School of Pharmacy, Jiangsu University, No. 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China

Email: njyuqingtong@hotmail.com

Part 2 Personal Profile

Dr. Qingtong Yu is an Assistant Research Fellow at the School of Pharmacy, Jiangsu University. He received his Ph.D. degree in Microbial and Biochemical Pharmacy from China Pharmaceutical University in December 2015, conducted postdoctoral research at the School of Pharmacy, Jiangsu University from 2016 to 2018, and was a visiting scholar at Harvard Medical School from 2014 to 2015. His research focuses on bioactive oligosaccharides of natural origin and stem cell-based therapy, with particular emphasis on the roles of oligosaccharide-modified mesenchymal stem cells in sepsis, spinal cord injury and nerve regeneration, as well as the underlying signaling mechanisms such as PI3K-Akt-mTOR. He has presided over one Young Scientists Fund project of the Natural Science Foundation of Jiangsu Province and participated as a principal member in two General Programs of the National Natural Science Foundation of China. Over the past five years, he has published three SCI papers as the first author in journals such as Phytomedicine, Advanced Drug Delivery Reviews and ACS Applied Materials & Interfaces. He also contributed to a study that won the First Prize of Science and Technology Progress at the provincial/ministerial level awarded by the China General Chamber of Commerce (2017).

Part 3 Education

•2010.09–2015.12, China Pharmaceutical University, Microbial and Biochemical Pharmacy, Ph.D.

•2005.09–2010.06, Jiangsu University, Medical Laboratory Science, B.S.

Part 4 Work Experience

•2018.11–Present, School of Pharmacy, Jiangsu University, Assistant Research Fellow

•2016.04–2018.10, School of Pharmacy, Jiangsu University, Postdoctoral Researcher

•2014.02–2015.02, Harvard Medical School, Visiting Scholar

Part 5 Research Interests

1.Mechanisms of stem cell therapy and intervention for sepsis

2.Pharmacological effects and mechanisms of bioactive oligosaccharides from natural sources

3.Spinal cord injury and nerve regeneration repair

4.Drug screening based on 3D printing, organoids and microfluidic chip technology

Part 6 Research Achievements

6.1 Research Projects

•2022.07–2025.06 | Natural Science Foundation of Jiangsu Province, Young Scientists Fund “LBO-modified ectodermal mesenchymal stem cells for the treatment of sepsis” (BK20220529) | PI

•2024.01–2027.12 | National Natural Science Foundation of China, General Program “Targeted repair of the blood-brain barrier by human reprogrammed pericytes” (82373820) | Participant

•2022.01–2025.12 | National Natural Science Foundation of China, General Program “Construction and application of an anti-stroke traditional Chinese medicine screening model based on 3D printing-organoid-microfluidic chip technology” (82173785) | Participant

6.2 Publications

Journal article format: Author (self in bold), Co-author(s). Article title [J]. Journal Name, Year, Volume(Issue): Page range.

1.Qingtong Yu, Linzhi Zhang, Zhe Wang, Qilong Wang, Xuan Sun, Wenwen Deng, Xia Cao, Jiangnan Yu, Ximing Xu. Anti-inflammatory oligosaccharide licensed mesenchymal stem cells allow prolonged survival of septic rats via the promotion of glutathione synthesis[J]. Phytomedicine, 2024, 135. (IF: 8.3, first author)

2.Linzhi Zhang, Zhe Wang, Xuan Sun, Wanjing Rong, Wenwen Deng, Jiangnan Yu, Ximing Xu, Qingtong Yu. Nasal mucosa-derived mesenchymal stem cells prolonged the survival of septic rats by protecting macrophages from pyroptosis[J]. Cellular Immunology, 2024, 401-402: 104840.

3.Qingtong Yu, Qilong Wang, Linzhi Zhang, Wenwen Deng, Xia Cao, Zhe Wang, Xuan Sun, Jiangnan Yu, Ximing Xu. The applications of 3D printing in wound healing: The external delivery of stem cells and antibiosis[J]. Advanced Drug Delivery Reviews, 2023, 197. (IF: 17.6, first author)

4.Zhe Wang, Xingxing Zhang, Deming Lv, Sucheng Cao, Guang Yang, Zhijian Zhang, Qingtong Yu. Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway[J]. Immunologic Research, 2023, 10(7).

5.Qingtong Yu, Mingchun Liao, Congyong Sun, Qijian Zhang, Wenwen Deng, Xia Cao, Qilong Wang, Emmanuel Omari-Siaw, Shiqi Bi, Zhijian Zhang, Jiangnan Yu, Ximing Xu. LBO-EMSC Hydrogel Serves a Dual Function in Spinal Cord Injury Restoration via the PI3K-Akt-mTOR Pathway[J]. ACS Applied Materials & Interfaces, 2021, 13(48): 48365-48377. (IF: 8.2, first author)

6.3 Monographs and Textbooks

•Shanshan Tong, Jiangnan Yu (Ed.). Pharmaceutical Analysis [M]. Zhenjiang: Jiangsu University Press, 2018. Qingtong Yu (5/7)