Part 1 Basic Information

Name: Guofan Jin

Address: School of Pharmacy, Jiangsu University, No. 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China

Email: 1000004770@ujs.edu.cn or organicboron@ujs.edu.cn

Part 2 Personal Profile

Dr. Guofan Jin is an Professor and Master's Supervisor at the School of Pharmacy, Jiangsu University. His research focuses on Engage in the design and synthesis of new anti-cancer drugs for BNCT (Boron Neutron Capture Therapy), the design and synthesis of BODIPY small molecule fluorescent targeting probes, the design and synthesis of organic light-emitting materials (Organic Light-Emitting Diodes, OLED), and the research and development of natural Chinese medicine (curcumin, quercetin, and emodin, etc.) fluorescent targeting nanomedicines and delivery systems. He has published over 60 papers in peer-reviewed journals, including Advances in Colloid and Interface Science(IF=23.7)、Advanced Healthcare Materials(IF=11) and International Journal of Biological Macromolecules(IF=8.7). He serves as a reviewer for "Advances in Colloid and Interface Science" and "Advanced Healthcare Materials", and currently serves as the deputy editor-in-chief of "Chinese Cosmetics Science".

Part 3 Education

•2006.09—2009.06 Wonkwang University, South Korea，Chemistry Major，Ph.D.

•2004.09—2006.06 Wonkwang University, South Korea，Chemistry Major，M.S.

•2000.09—2004.06 Yanbian University，Pharmacy Major，B.S.

Part 4 Work Experience

•2017.04- Present, School of Pharmacy, Jiangsu University, Professor and Master's Supervisor

•2014.06-2017.02, Wonkwang University, South Korea, College of Natural Science and Technology, research professor

•2011.10-2014.04, Korea University, South Korea, Post-doctoral (research professor)

•2009.07–2011.10, OCT-Medical Research Institute of South Korea (Co., LTD.), Research Group Leader

Part 5 Research Interests

1.Synthetic design and research of drugs for treating cancer and tumors: mainly including 1) The design of new anti-cancer drugs such as BNCT, 2) the development of new heterocyclic anti-tumor drugs such as pyrimidine and quinolone, and 3) the development of sulfonamide anti-tumor drugs.

2.Organic light-emitting materials (Orgainc Light Emitting Diodides, OLED) synthesis and research and development: (ETL design, HTL, EML and R, G, B dopant materials).

3.Research on BODIPY Fluorescent Targeted Probes: 1) Design of water-soluble dynamic autonomous nano-targeted fluorescent probes, 2) Design of protein-expressing targeted probes.

4.Design, synthesis and application of fluorescent Targeted nanomedicine and delivery system carriers.

Part 6 Research Achievements

6.1 Publications

1.Wang, ZN; Su, P; Guofan Jin*. Photophysical behavior of sulfur-oxidized sulfone and trifluoromethyl-BODIPY: Insight into the relationship between crystal structure and tumor cell imaging. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY. 2026-5-11 (SCI Q1, IF=4.5)

2.Chai, TT; Zhang, MT; Su, P; Lu, CC; Guofan Jin*. pH-Triggered and Targeted Delivery of Curcumin: From Dendritic Polymers to Natural and Synthetic Nanocarriers. ADVANCED HEALTHCARE MATERIALS. 2026-04-22 (SCI TOP Q1， IF=11)

3.Su, P; Chai, TT; Wang, ZN; Lu, CC; Guofan Jin*. Self-assembling nanoscale platforms for curcumin delivery using cerebroprotein hydrolysate/crown ether/quaternary ammonium salts/ phospholipid: pH-responsive release, in vivo targeting real-time monitoring and visualization analysis. EUROPEAN POLYMER JOURNAL. 2026-01-09 (SCI Q1, IF=6.8)

4.Su, P; Wang, ZN; Zhang, MT; Guofan Jin*. Oral polymer nanoparticles containing curcumin and berberine hydrochloride based on cerebroprotein hydrolysate-phospholipid crown ether self-assembly: evaluation of nanoparticle properties and in vivo targeting. EUROPEAN POLYMER JOURNAL. 2025-08-11 (SCI Q1, IF=6.8)

5.Wang, ZN; Su, P; Lu, CC; Guofan Jin*. A carrier-free rigid fluorescent small molecule CF3/S-containing BODIPY probe: Design and synthesis, tumor cell imaging and biological activity evaluation. DYES AND PIGMENTS. 2025-04-11 (SCI Q1, IF=4.2)

6.Su, P; Wang, ZN; Lu, CC; Guofan Jin*. A novel piperazine-linked BODIPY-pyrimidine anti-tumor fluorescent active drug: targeting mechanism, real-time dynamic imaging and delivery effect of DSPC/DPIC nanoparticles. BIOORGANIC CHEMISTRY. 2025-11-03 (SCI Q1, IF=5.1)

7.Lü, ZY; Chai, TT; Lu, CC; Guofan Jin*. Asymmetrical carbazole-b enzonitrile-base d TADF emitters designe d by alternate donor-acceptor strategy. CHINESE CHEMICAL LETTERS.2025-04-08 (SCI TOP Q1, IF=9.5)

8.Mengtong Zhang; Guofan Jin*. Multi-component driven fluorescence composite nanospheres coating strategy: Spectral properties, release, tumor imaging and bioactivity evaluation in a simulated gastrointestinal microenvironment. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. (2025), 125858. (SCI Q1, IF=4.5)

9.Chan, TT; Guofan Jin*. Based on sodium alginate coatings and dendritic copolymeric modification of curcumin delivery system: pH-sensitive nanospheres and strong tumor cytotoxicity. International Journal of Biological Macromolecules. (2025), 112428. 137962 (SCI Q1, IF=8.9)

10.Chan, TT; Guofan Jin*. Curcumin/nido-carborane complexes incorporated with crown ether/sodium alginate encapsulated drug delivery strategies exhibit pH-responsive release and enhanced in vitro anti-tumor activity. DYES AND PIGMENTS. (2024), 112428 (SCI Q1, IF=4.2)

11.Liu Y; Guofan Jin*. Rigid symmetric Rhodamine fluorescent dyes as fast selective detection of aluminum and iron ions applied to cell imaging. JOURNAL OF MOLECULAR STRUCTURE. (2024), 1312, 138552 (SCI Q1, IF=4.2)

12.Zhou, M; Guofan Jin*. Design, synthesis, and antitumor activity evaluation of BF3-o, m, p-phenylenediamine bridged with pyrimidine-indole BF3 adduction derivatives. MOLECULAR DIVERSITY. (2024), 07, 28 (SCI Q1, IF=4.3)

13.Chan, TT; Guofan Jin*. A novel pH-sensitive drug carrier system based on 18-crown ether-6/ sodium alginate for curcumin/nido-carborane encapsulation: Studies of release properties, cell imaging and bioactivity evaluation. DYES AND PIGMENTS. (2024), 229 (SCI Q1, IF=4.2)

14.Zhang MT; Guofan Jin*. Polymorphic strategies for encapsulating polyindole@nido-carborane fluorescent polymeric nanocapsules: Their release, imaging, and biological evaluation in the gastrointestinal microenvironment. EUROPEAN POLYMER JOURNAL. (2024), 215 (SCI Q1, IF=6.8)

15.Zhou, M ; Liu, Y ; Wang, S ; Feng, JK ; Ni, HY ; Lu, CC ; Guofan Jin*. Design, synthesis, cell imaging, and bioactivity assessment of novel Rhodamine-Pyrimidine nido-carborane derivatives as fluorescent anticancer agents. JOURNAL OF MOLECULAR STRUCTURE. (2024), 1299, 137211 (SCI Q1, IF=4.9)