Part 1 Basic Information

Name: Ruijiang Liu

Address: School of Pharmacy, Jiangsu University, No. 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China

Email: 1000003001@ujs.edu.cn

Part 2 Personal Profile

Dr. Ruijiang Liu is an Associate Professor and Master's Supervisor at the School of Pharmacy, Jiangsu University. His research focuses on construction and evaluation of nanomedicine, construction of electrochemical nano-biosensors and detections of tumor markers, fabrications and applications of magnetic functional nano-spatial materials. He has presided and participated in over 50 projects, published more than 120 SCI-indexed articles, among which he is the first author or corresponding author in over 90 articles, and he has also obtained 17 Chinese invention patents.

Part 3 Education

•2010.09—2013.12 Jiangsu University, Materials science, Ph.D.

•2002.09—2004.06 Nanjing Technology University, Chemical engineering, M.S.

•1995.09—1999.07 Yantai University, Chemical engineering, B.S.

Part 4 Work Experience

•2013.08—Present, School of Pharmacy, Jiangsu University, Associate Professor and Master's Supervisor

•2006.08—2013.07 School of Pharmacy, Jiangsu University, Lecturer

•2004.07—2006.07 College of Biological and Environmental Engineering, Jiangsu University, Teaching assistant

Part 5 Research Interests

1.Construction of electrochemical nano-biosensors and detections of tumor markers

2.Construction and evaluation of novel dual targeting drug delivery Nano-system

3.Fabrications and applications of magnetic functional nano-spatial materials

Part 6 Research Achievements

6.1 Research Projects

•2026.01—2028.12｜Enterprise cooperation project “Construction of a novel drug delivery system based on magnetic heterogeneous nanomaterials and development of detection technologies for tumor markers”（Grant No. HX20260030）｜Principal Investigator

•2025.01—2026.10｜Enterprise cooperation project “The development of a novel type of label-free and magnetic self-assembled electrochemical biosensor for CYFRA 21-1 gene detection”（ Grant No. HX20250099）｜Principal Investigator

•2023.04—2025.04｜Enterprise cooperation project “Development of novel technologies for the preparations and applications of magnetic nano-spatial materials（Grant No. HX20230236）｜Principal Investigator

•2021.11-17—2022.12｜Enterprise cooperation project “Development of a magnetic label-free CYP2C9*3 gene electrochemical biosensor”（ Grant No. HX20210827）｜Principal Investigator

•2021.06—2023.06｜National energy project “Developments of a shaping magnetic collector and the magnetic reuse component”（ Grant No. HX20210452）｜Principal Investigator

•2020.10—2022.10｜National energy projects “Development of non-standard components for the interception and purification of VOC / Development of non-standard components for cold-state adjustable magnetic interceptor / Development of a micro-column network devices for recycling and separation”（ Grant Nos. HX20200579 / HX20200580 / HX20200581）｜Principal Investigator

•2016.05—2017.05｜China Postdoctoral Research Funding Program “Construction of delivery system for siRNA loaded on magnetic Fe₃O₄/Fe₂O₃ composite nanotubes” （Grant No. 2016M591778）｜Principal Investigator

•2016.03—2018.03｜Enterprise cooperation project “Preparation of magnetic nano-space materials for development of wastewater treatment technology” （Grant No. HX20160071）｜Principal Investigator

•2015.07—2016.12｜Postdoctoral Research Funding Project of Jiangsu Province “Fabrication of magnetic ferric oxide nanotubes for the construction of siRNA loading and delivery” （Grant No. 1501086C）｜Principal Investigator

6.2 Publications

[1]Yixing Li^#, Zhongjun Pan^#, Chen Ling, Jiahao Yuan, Shasha Li*, Ruijiang Liu*. Construction of targeted paclitaxel delivery nanosystem and its apoptosis mechanism on A549 cells. Biomaterials Advances, 2026, 187(10): 214951. (SCI, IF=6.7)

[2]Yuxuan Bai^#, Zhixiang Lv^#, Xuesong Cheng, Yawen Su, Yongjin Li, Dawei He, Ruijiang Liu^*. Magnetic aptamer-functionalized electrochemical nano-biosensor for the detection of circulating tumor DNA. Arabian Journal of Chemistry, 2026, 19(3): 7012025. (SCI, IF=5.3)

[3]Qingxiang Wang^#, Boyi Jiang^#, Liping Wu, Ruiping Chen, Yawen Su, Yongjin Li*, Aolin He*, Ruijiang Liu*. An electrochemical biosensor with indicator-free and magnetically self-assembly for supersensitive determination of PIK3CA gene. Microchemical Journal, 2025, 219(12): 116148. (SCI, IF=5.2)

[4]Mingyi Ma^#, Zhongjun Pan^#, Ziye Zhu, Chen Ling, Jiahao Yuan, Xiangdong Huo*, Shasha Li*, Ruijiang Liu*. Enhanced cancer therapy using modified magnetic α-Fe₂O₃/Fe₃O₄ nanorods: Dual role in curcumin delivery and ferroptosis induction. Colloids and Surfaces B: Biointerfaces, 2025, 252 (8): 114689. (SCI, IF=5.9)

[5]Qingxiang Wang^#, Hezhong Ouyang^#, Jingyi Zhou, Hexiao Zhang, Aolin He*, Ruijiang Liu*. Development and Performance Evaluation of a Magnetic Self-Assembled Electrochemical Biosensor based on α-Fe₂O₃/Fe₃O₄ Heterogeneous Nanorods for Supersensitive Detection of KRAS. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2025, 715(6): 136624. (SCI, IF=5.4)

[6]Zhihao Xu^#, Hezhong Ouyang^#, Sihan Zhao, Xinyu Wang, Xiangdong Huo*, Dawei He*, Ruijiang Liu*. Electroactive Fe₃O₄/α-Fe₂O₃@Au nanocomposites driven label‑free electrochemical aptasensor with magnetic self‑assembly for rapid quantification of alpha‑fetoprotein. Microchimica Acta, 2025, 192: 361. (SCI, IF=5.4)

[7]Haoda Zhang^#, Zhixiang Lv^#, Hexiao Zhang, Yunxiao Zhang, Dawei He*, Ruijiang Liu*. Ultrasensitive detection of PrP^C in human serum using label-free electrochemical biosensor based on α-iron trioxide/ferriferrous oxide magnetic nanocomposites. Microchemical Journal, 2025,212(5): 113369. (SCI, IF=5.2)

[8]Yao Yue^#, Min Liu^#, Mingyi Ma, Zhihao Xu, Haoda Zhang, Qingxiang Wang, Ruijiang Liu*. CRISPR/Cas14a integrated with DNA walker based on magnetic self-assembly for human papillomavirus type 16 oncoprotein E7 ultrasensitive detection. Biosensors & Bioelectronics, 2025, 272(3): 117135. (SCI, IF=11.8)

[9]Qingxiang Wang^#, Min Liu^#, Jihong Zhao, Jiahao Yuan, Shasha Li*, Ruijiang Liu*. Development of a magnetic α‑Fe₂O₃/Fe₃O₄ heterogeneous nanorod-based electrochemical biosensing platform for HPV16 E7 oncoprotein detection. International Journal of Biological Macromolecules, 2025, 284(1): 138085. (SCI, IF=8.7)

[10]Zhihao Xu^#, Hezhong Ouyang^#, Haoda Zhang, Lei Sun, Shasha Li*, Ruijiang Liu*. Ultrafast and Precisely Detection of ProGRP in Human Serum Using Label-Free Electrochemical Biosensor based on α-Fe₂O₃/Fe₃O₄ heterogeneous nanosheets. Ceramics International, 2024, 50(23): 50054-50066. (SCI, IF=5.6)

[11]Jie Wang^#, Min Liu^#, Jiawei Tang, Yaping Yang, Nan He, Shasha Li*, Ruijiang Liu*. Construction of Electrochemical Biosensor Based on Magnetic Fe₃O₄/α-Fe₂O₃ Heterogeneous Nanorods for the Sensitive Detection of MUC1 Mucoprotein. Ceramics International, 2024, 50: 10706-10714. (SCI, IF=5.6)

[12]Yun Ni^#, Xiu Chen^#, Chen Ling, Ziye Zhu, Yao Yue, Jie Wang, Aolin He*, Ruijiang Liu*. Label-Free Electrochemical Biosensor Based on Peptide Nucleic Acid Functionalized α-Fe₂O₃/Fe₃O₄ Nanosheets for Sensitive Detection of CYP2C19*2 Gene. Microchimica Acta, 2023, 190: 189. (SCI, IF=5.3)

[13]Ruijiang Liu^#, Yanling Zhang^#, Peng Deng^#, Wei Huang, Ruitong Yin, Lulu Yu, You Li, Shaoshuai Zhang, Yun Ni, Chen Ling, Ziye Zhu, Shaobo Wu*, Shasha Li*. Construction of targeted delivery system for curcumin loaded on magnetic α-Fe₂O₃/Fe₃O₄ heterogeneous nanotubes and its apoptosis mechanism on MCF-7 cell. Biomaterials Advances, 2022, 136: 212783. (SCI, IF=7.9)

[14]Yanling Zhang^#, Min Liu^#, Shuai Pan, Lulu Yu, Shaoshuai Zhang, Ruijiang Liu*. A magnetically induced self-assembled and label-free electrochemical aptasensor based on magnetic Fe₃O₄/Fe₂O₃@Au nanoparticles for VEGF₁₆₅ protein detection. Applied Surface Science, 2022, 580: 152362. (SCI, IF=6.7)

[15]You Li, Tengchao Wang, Shaoshuai Zhang, Yanling Zhang, Lulu Yu, Ruijiang Liu*. Adsorption and electrochemical behavior investigation of methyl blue onto magnetic Ni_xMg_(1-x)Fe₂O₄ nanoparticles prepared via the rapid combustion process. Journal of Alloys and Compounds, 2021, 885: 160969. (SCI, IF=6.371)

[16]Ruijiang Liu^#, Zhixiang Lv^#, Xiao Liu, Wei Huang, Ruitong Yin, Lulu Yu, You Li, Yanling Zhang, Shaoshuai Zhang, Rongzhu Lu, Yongjin Li*, Shasha Li*. Improved delivery system for celastrol-loaded magnetic Fe₃O₄/Fe₂O₃ heterogeneous nanorods: HIF-1α-related apoptotic effects on SMMC-7721 cell. Materials Science & Engineering C-Materials for Biological Applications, 2021, 125: 112103. (SCI, IF=8.457)

[17]Ruijiang Liu^#, Guoxiang Rong^#, Yanghua Liu, Wei Huang, Dawei He*, Rongzhu Lu*. Delivery of apigenin-loaded magnetic Fe₂O₃/Fe₃O₄@mSiO₂ nanocomposites to A549 cells and their antitumor mechanism. Materials Science & Engineering C-Materials for Biological Applications, 2021, 120: 111719. (SCI, IF=8.457)

[18]Ruijiang Liu*^,#, Shuai Pan^#, Min Liu^#, Wei Huang, Zhixiang Lv, Aolin He^*. A label-free electrochemical biosensor with magnetically induced self-assembly for the detection of CYP2C9*3 gene. Applied Surface Science, 2021, 537: 147868. (SCI, IF=7.392)

[19]Ruijiang Liu*, Wei Huang, Shuai Pan, You Li, Lulu Yu, Dawei He^*. Covalent immobilization and characterization of penicillin G acylase on amino functionalized magnetic Fe₂O₃/Fe₃O₄ heterogeneous nanoparticles prepared via a facile solution-combustion process. International Journal of Biological Macromolecules, 2020, 162: 1587-1596. (SCI, IF=6.953)

[20]Wei Huang, Shuai Pan, You Li, Lulu Yu, Ruijiang Liu*. Immobilization and characterization of cellulase on hydroxy and aldehyde functionalized magnetic Fe₂O₃/Fe₃O₄ nanocomposites prepared via a novel rapid combustion process. International Journal of Biological Macromolecules, 2020, 162: 845-852. (SCI, IF=6.953)

6.3 Monographs and Textbooks

•Ruijiang Liu（subeditor）, 《Preparation and Synthesis Experiments of Inorganic Materials》（"Twelve and Five" General Higher Education Undergraduate Curriculum Textbook），Chemical Industry Press，2015-09。

6.4 Patents and Software Copyrights

Authorized patents：

[1] A method for the fabrication of magnetic Fe₃O₄/α-Fe₂O₃ nanorods: ZL 202310056316.1 [P]. 2025-09-02.

[2] A type of VEGF₁₆₅ protein probe, and its construction method and application: ZL 202111027624.9 [P]. 2024-04-09.

[3] A type of self-assembly and label-free magnetic CYP2C9*3 gene probe and its preparation method: ZL 202010716321.7 [P]. 2024-03-19.

[4] A type of magnetic heterogeneous nanomaterials and its preparation method: ZL 202111175872.8 [P]. 2024-01-26.

[5] A method for the preparation of rod-like Fe₃O₄@Fe₂O₃ magnetic nanocomposites: ZL 202010770537.1 [P]. 2023-10-10.

[6] A type of Fe₃O₄/Fe₂O₃ magnetic heterogeneous nanotube and its preparation method ZL 202010716294.3 [P]. 2023-07-04.

[7] A magnetically induced self-assembly electrochemical biosensor for the sensitive detection of trace nickel ions: ZL 202110659691.6 [P]. 2023-05-05.

[8] A spray calcination device: ZL 202122429869.6 [P]. 2022-04-08.

[9] A type of FeOOH nanoflagellate and its preparation method: ZL 201811162387.5 [P]. 2021-06-18.

[10] A type of ice-berg-shaped ZnO micro-material and its preparation method: ZL 201811480962.6 [P]. 2020-11-20.

[11] A type of hedgehog-shaped FeOOH micro-material and its preparation method: ZL201810574611.5 [P]. 2020-07-31.

[12] A method for the preparation of α-Fe₂O₃ magnetic nanorods: ZL 201611131663.2 [P]. 2018-12-14.

[13] A type of cactus ball-shaped Fe₃O₄/Fe₂O₃ magnetic heterogeneous nanomaterial and its preparation method: ZL 201610627577.4 [P]. 2018-01-16.

[14] A method for the preparation of rod-like Fe₃O₄/Fe₂O₃ magnetic nanocomposites: ZL 201610229201.8 [P]. 2017-12-15.

[15] A method for the preparation of rounded Mn ferrite magnetic nanosheets: ZL 201610228400.7 [P]. 2017-04-26.

[16] A method for the fabrication of Ni ferrite magnetic nanorods: ZL 201510235761.X [P]. 2017-04-12.

[17] A method for the preparation of magnetic Fe₂O₃/Fe₃O₄ heterogeneous nanoparticles: ZL 201510235739.5 [P]. 2016-08-31.