Part 1 Basic Information

Name: Wen Chongwei

Address: School of Pharmacy, Jiangsu University, No.301 Xuefu Road, Zhenjiang, Jiangsu 212013, China

Tel: 0511-85038201

Email: wenchw@ujs.edu.cn

Part 2 Personal Profile

Dr. Wen Chongwei is an Associate Professor and Master’s Supervisor at the School of Pharmacy, Jiangsu University. He has long been engaged in research on molecular identification of traditional Chinese medicine (TCM), TCM quality control and TCM resource development by adopting techniques including biochemistry, cell biology, molecular biology, proteomics, peptidomics and fingerprinting. He has presided over or participated in 10 national and provincial research projects as well as 3 municipal-level research projects. He has published more than 30 academic papers in authoritative domestic and international journals such as Pharmacognosy Research, Bioorganic & Medicinal Chemistry Letters, Journal of Agricultural and Food Chemistry and Food Science. He is a co-author of one textbook and holds 7 authorized national invention patents.

Part 3 Education

•2005.01–2006.12, University of California, Irvine, Neuropharmacology, Postdoctoral Fellow.

•1997.09–2002.12, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Biochemistry and Molecular Biology, Ph.D. (Combined Master’s and PhD Program)

•1989.09–1993.06, Peking University Health Science Center (formerly Beijing Medical University), Pharmacy, B.S.

Part 4 Work Experience

•2011.08–Present, School of Pharmacy, Jiangsu University, Associate Professor and Master's Supervisor

•2004.07–2011.07, School of Pharmacy, Jiangsu University, Lecturer

•2003.01–2004.06, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Research Assistant

Part 5 Research Interests

1.Develop molecular detection methods for the original species of Chinese medicinal materials using fingerprinting, DNA barcoding, molecular systematics and other technologies；

2.Screen quality markers of traditional Chinese medicine (TCM) and elucidate the effective substance basis. This work aims to establish a traceable and systematic TCM quality control system to achieve effective quality evaluation of Chinese medicinal materials and TCM preparations；

3.Explore active components from medicinal resources and study the comprehensive utilization of by-products of Chinese medicinal materials, so as to provide theoretical and technical support for the conservation, rational exploitation and sustainable industrial application of TCM resources.

Part 6 Research Achievements

6.1 Research Projects

•2015.12-2018.09｜Key Project at Central Government Level “Development of Specification and Grade Standards for Bombyx Batryticatus”（Grant No.2060302-1509-21）｜Ministry of Finance of the People's Republic of China｜Principal Investigator

•2020.01-2023.12｜Natural Science Research Project of Anhui Educational Committee “Research on Chemical Basis, Genetic Diversity Analysis, and Anti-inflammatory Activity of Angelicae Dahuricae Radix”（Grant No. KJ2019ZD80）｜Department of Education of Anhui Province｜Participant (1st within the university)

•2023.01-2026.12｜General Program of the National Natural Science Foundation of China: “Analysis Of the Key Hydroxylation Processes in the Biosynthetic Pathway of DNJ Polyhydroxy Alkaloids in Mulberry Leaves” （Grant No. 82274040）｜NSFC｜Participant (3rd)

•2019.10-2023.06｜Key Project at Central Government Level“Development of Specification and Grade Standards for Rubi Fructus, Panacis Japonici Rhizoma, and Visci Herba”（Grant No: 2060302-1906-12, 13）｜Ministry of Finance of the People's Republic of China｜Participant (4th)

•2018.12-2023.06｜National Key R&D Program of China“Research on New Ethnic/Folk Traditional Chinese Medicines”（Grant No.2018YFC1706105）｜Ministry of Science and Technology of the People's Republic of China｜Participant (5th within the university)

•2016.01-2019.12｜General Program of the National Natural Science Foundation of China: “Studies on the mechnism of quality change of mulberry leaves after frost” （Grant No. 8157141409）｜NSFC｜Participant (4th)

•2014.01–2017.12｜National Natural Science Foundation of China General Program “Construction and Application of CYP450 Gene Knockout Rat Models Based on TALEN Technology”（Grant No. 81373480）｜NSFC｜Participant (3rd)

•2012.01–2014.12｜National Natural Science Foundation of China Young Scientists Fund “Extrahepatic Metabolism and Toxicology of Triptolide Based on XH-CL Gene Knockout Mouse Models”（Grant No. 81102522）｜NSFC｜Participant (3rd)

•2011.01–2013.12｜National Natural Science Foundation of China General Program “Construction of three-dimensional nano gene delivery system of Yamanaka factors and its research on induced pluripotent stem cells”（Grant No. 81072586）｜NSFC｜Participant (3rd)

•2008.01–2010.12｜National Natural Science Foundation of China General Program “Research on non-viral three-dimensional nano gene delivery systems”（ Grant No. 30772661）｜NSFC｜Participant (4th)

6.2 Publications

1. Tang Jian, Zhou Ping, Sun Huifang, Xu Xiuquan, Wen Chongwei, Xia Haiping. Antioxidant, Stimulating Telomerase and Anxiolytic Activities of Polysaccharide Isolated from Sargentodoxa cuneata [J]. Pharmacognosy Research, 2025, 17(3): 1020-1028.（SCI）

2. Tang Jian, Jiang Chunbao, Zhu Yuling, Wen Chongwei, Xu Xiuquan, Xia Haiping. Design, molecular docking and suppression on NF-κB activity of sinomenine hybrid derivatives [J]. Bioorganic & Medicinal Chemistry Letters, 2025, 128: 130348.（SCI）

3. Yu Yongfei Wang Qiaoyu, Zhang Yunxiao, Feng Shuo, Xia Zhenxinyu, Wen Chongwei, Tang Jian. Optimization of preparation process of ACE inhibitory peptides from Bombyx Batryticatus ethanol-soluble proteins by response surface methodology [J]. Chinese Traditional Patent Medicine, 2025, 47(12): 4140-4144（PKUCCJ，CSCD）

4. Song Meiying，Wang Liyong，Wang Qiaoyu，Zhang Linsong，Xu Weidong，Tang Jian，Wen Chongwei. Study on establishment of protein grading fingerprint of Bombyx Batryticatus and its correlated molecules of geographical origin identification [J]. Natural Product Research and Development, 2023, 35(09): 1486-1494.（CSCD）

5. Liu Jia, Wan Jingqiong, Du Wenmin, Wang Dujun, Wen Chongwei, Wei Yuan, Ouyang Zhen. In-vivo functional verification of four related genes involved in the 1-deoxynojirimycin biosynthetic pathway in mulberry leaves [J]. Journal of Agricultural and Food Chemistry, 2021, 69(37): 10989-10998.（SCI）

6. Liu Jia, Wan Jingqiong, Wang Dujun, Wen Chongwei, Wei Yuan, Ouyang Zhen. Comparative transcriptome analysis of key reductase genes involved in the 1-Deoxynojirimycin biosynthetic pathway in mulberry leaves and cloning, prokaryotic expression, and functional analysis of MaSDR1 and MaSDR2 [J]. Journal of Agricultural and Food Chemistry, 2020, 68(44): 12345-12357.（SCI）

7. Wen Chongwei, Zhao Yeqing, Shi Li, Ouyang Zhen. Protein precipitation from egg white with polyethylene glycol and its application for ovalbumin separation [J]. Food Science, 2018, 39(01): 29-35.（EI，PKUCCJ）

6.3 Monographs and Textbooks

•Zheng Weijuan (Chief Editor). Modern Molecular Biology Experiments (2nd edition)[M]. Beijing: Higher Education Press, 2019. ISBN 978-7-04-050480-4 (Contributor).

•Zheng Weijuan (Chief Editor). Modern Molecular Biology Experiments (1st edition)[M]. Beijing: Higher Education Press, 2010. ISBN 978-7-04-029586-3 (Contributor)

6.4 Patents and Software Copyrights

•Wen Chongwei, Liu Ying, Zhang Linsong, Zhou Linhui, Li Mengxi, Xu Weidong, Pei Dan. A simple method for discovering differential proteins in Bombyx Batryticatus medicinal materials: 202110286852.1[P]. 2023-05-09

•Wen Chongwei, Ge Teng, Zhao Yeqing, Zhou Huilian, Shi Li. A method for co-preparing ovalbumin and ovotransferrin: 201610300962.8[P]. 2019-08-02

•Wen Chongwei, Zhao Yeqing, Zhou Huilian, Ouyang Zhen, Chen Rongrong. A purification method suitable for large-scale preparation of food-grade ovalbumin: 201510342990.1[P]. 2019-05-31

•Wen Chongwei, Zhao Yeqing, Zhou Huilian, Ouyang Zhen, Wang Xiaoyan. A method for increasing the expression level of soluble recombinant prokineticin 2β in Escherichia coli: 201510516845.0[P]. 2019-04-02

•Wen Chongwei, Ning Degang. A mild and efficient method for disrupting Escherichia coli cells: 201310429369.X[P]. 2015-12-09

•Wen Chongwei, Wang Yali. A method to separate soluble and insoluble proteins from Escherichia coli cells: 201310431724.7[P]. 2015-04-22

•Wen Chongwei, Ning Degang, Xu Weidong. A method for co-isolation and preparation of egg white lysozyme and active proteins: 201310080459.2[P]. 2015-03-04