Part 1 Basic Information

Name: Shan Lu

Address: School of Pharmacy, Jiangsu University, No. 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China

Email: 153066414@qq.com

Part 2 Personal Profile

Dr. Shan Lu is a Professor and Master's Supervisor at the School of Pharmacy, Jiangsu University. Her research focuses on natural products and medicinal chemistry.

Part 3 Education

•2012.10—2017.03, Kyoto University, Natural Product Chemical biology, Ph.D.

•2007.09—2010.06, Second Military Medical University, Natural Product, M.S.

•2002.09—2006.06, China Pharmaceutical University, Chinese Traditional Medicine, B.S.

Part 4 Work Experience

•2021.08-Present, School of Pharmacy, Jiangsu University, Professor

•2018.11-2021.07, Department of Chemistry, Biology and Marine Science, Faculty of Science, University of the Ryukyus, Assistant Professor

•2017.04-2018.10, Division of Bioinformatics and Chemical Genomics, Graduate School of Pharmaceutical Sciences, Kyoto University, PostDoc

Part 5 Research Interests

1.Screening and structure identification of complex nature products

2.Structure identification of complex nature products by NMR and LCMS

3.Natural products-based chemical biology for drug discovery.

4.Synthesis of bioactive natural products

Part 6 Research Achievements

6.1 Research Projects

•2022-2024, National Natural Science Foundation of China, Principal Investigator

•2019-2020, University of the Ryukyus Research Project Promotion Grant for Foreign Researchers, Principal Investigator

6.2 Publications

1.Mao, D., Su, X., Liu, C., Wei, B., Yang, Y., Li, X., Chen, C., Zou, Y., Ling, Z., Kakeya, H., Ding, L., Lu, S.* Structure Revision, Absolute Configuration Determination, and Biological Evaluation of Furanonaphthoquinone I. J. Nat. Prod. 2026, 89, 992-999.

2.Zhang,Y., Ren, L., Kakeya, H., Liu, C.,* Mao, D.,* Lu, S.* Recent Progress in Nonanolides of Natural Origin: Structures, Synthesis, Biosynthesis, and Bioactivities. Chem. Rec. 2025, 25, e202500123.

3.Mao, D, Wei, B., Liu, C., Zhang, B., Zhang, Z., Zhang, Y., Li, Z., Ding, B., Ye, H., Wang, J., Sun, L., Gai, Y., Yu, P., Kakeya, H., Lu, S.* Discovery, total synthesis, and biological evaluation of tyrcinnamins as antibacterial agents and tyrosinase activators. Eur. J. Med. Chem. 2025, 291, 117665.

4.Lu S., Nishimura S., Takenaka K., Ito M., Kato T., Kakeya H. Discovery of presaccharothriolide X, a retro-Michael reaction product of saccharothriolide B, from the rare actinomycete Saccharothrix sp. Org. Lett. 2018, 20 (15), 4406-4410.

5.Lu S., Nishimura S., Hirai G., Ito M., Kawahara T., Izumikawa M., Sodeoka M., Shin-ya K., Tsuchida T., Kakeya H. Saccharothriolides A-C, novel phenyl-substituted 10-membered macrolides isolated from a rare actinomycete Saccharothrix sp. Chem. Commun. 2015, 51(38), 8074-8077.